Keratins Are Going Nuclear

Ryan P. Hobbs, Justin T. Jacob, Pierre A. Coulombe

Research output: Contribution to journalComment/debate

Abstract

Previously thought to reside exclusively in the cytoplasm, the cytoskeletal protein keratin 17 (K17) has been recently identified inside the nucleus of tumor epithelial cells with a direct impact on cell proliferation and gene expression. We comment on fundamental questions raised by this new finding and the associated significance.

Original languageEnglish (US)
Pages (from-to)227-233
Number of pages7
JournalDevelopmental Cell
Volume38
Issue number3
DOIs
StatePublished - Aug 8 2016

ASJC Scopus subject areas

  • Developmental Biology

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    Hobbs, R. P., Jacob, J. T., & Coulombe, P. A. (2016). Keratins Are Going Nuclear. Developmental Cell, 38(3), 227-233. https://doi.org/10.1016/j.devcel.2016.07.022