Kaposi's sarcoma presenting as a protracted multisystem illness in an adolescent liver transplant recipient

N. U. Yokois, E. J. Perlman, Paul Colombani, B. Wise, Kathleen Schwarz

Research output: Contribution to journalArticle

Abstract

Kaposi's sarcoma (KS) is a common malignancy in patients with acquired immunodeficiency syndrome (AIDS), classically appearing as red to purple plaques containing small papules and nodules. We report our experience with an adolescent orthotopic liver transplant recipient who presented with an unusual presentation of KS. The patient had a protracted multisystem illness that began with hemolytic anemia, fevers, and fatigue and progressed to pancreatitis, sinusitis, lymphadenopathy, and mouth ulcers. The diagnosis was made by a lymph node biopsy that was performed to evaluate for Epstein-Barr virus. The classical subcutaneous nodules characteristic of KS did not become evident until shortly before the patient died. We present this case to emphasize that KS in pediatric liver transplant patients can present as a multisystem disease that progresses to disseminated organ involvement before the characteristic subcutaneous manifestations are evident.

Original languageEnglish (US)
Pages (from-to)541-544
Number of pages4
JournalLiver Transplantation and Surgery
Volume3
Issue number5
StatePublished - 1997

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Kaposi's Sarcoma
Liver
Oral Ulcer
Hemolytic Anemia
Sinusitis
Human Herpesvirus 4
Pancreatitis
Fatigue
Acquired Immunodeficiency Syndrome
Fever
Lymph Nodes
Pediatrics
Transplants
Biopsy
Transplant Recipients
Neoplasms

ASJC Scopus subject areas

  • Hepatology
  • Surgery

Cite this

Kaposi's sarcoma presenting as a protracted multisystem illness in an adolescent liver transplant recipient. / Yokois, N. U.; Perlman, E. J.; Colombani, Paul; Wise, B.; Schwarz, Kathleen.

In: Liver Transplantation and Surgery, Vol. 3, No. 5, 1997, p. 541-544.

Research output: Contribution to journalArticle

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