Joint estimation of image and deformation parameters in motion-corrected PET

M. W. Jacobson, J. A. Fessler

Research output: Contribution to journalConference articlepeer-review


We consider an emission tomography reconstruction problem in which projection measurements from several time frames are available. Two strategies for doing motion-corrected image reconstruction are compared. In the first strategy, separate images are reconstructed from the measurements at each time frame. They are then consolidated by post-registration and averaging procedures. In the second strategy, we incorporate parameters to describe the effects of motion into the statistical model of the projections. Joint maximum likelihood estimation of image and motion parameters is then carried out. Each of these strategies involves the minimization of non-convex cost functions. Accordingly, we also propose some relevant optimization algorithm design options.

Original languageEnglish (US)
Article numberM16-8
Pages (from-to)3290-3294
Number of pages5
JournalIEEE Nuclear Science Symposium Conference Record
StatePublished - Dec 1 2003
Event2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference - Portland, OR, United States
Duration: Oct 19 2003Oct 25 2003

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


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