Abstract
This article provides practical recommendations developed from the International Society of Gynecological Pathologists Endometrial Carcinoma Project to address 4 issues that may arise in the diagnosis of uterine corpus low-grade endometrioid carcinoma: (1) The distinction between atypical hyperplasia and low-grade endometrioid carcinoma. (2) The distinction between low-grade endometrioid carcinoma and serous carcinoma. (3) The distinction between corded and hyalinized or spindle cell variants of low-grade endometrioid carcinoma and carcinosarcoma. (4) The diagnostic criteria for mixed endometrial carcinomas, a rare entity that should be diagnosed only after exclusion of a spectrum of tumors including morphologic variants of endometrioid carcinoma, dedifferentiated endometrial carcinoma, carcinosarcoma, and endometrial carcinomas with ambiguous morphology.
Original language | English (US) |
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Pages (from-to) | S25-S39 |
Journal | International Journal of Gynecological Pathology |
Volume | 38 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2019 |
Keywords
- Atypical hyperplasia
- Endometrial cancer
- Mixed carcinoma
- Serous carcinoma
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Obstetrics and Gynecology