Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates

George Panzak, Ralph Tarter, Srinivas Murali, JoAnn Switala, Sandra Lu, Brion Maher, David H. Van Thiel

Research output: Contribution to journalArticle

Abstract

Intensity of isometric muscle contractions was measured in alcoholic subjects with cirrhosis (N = 42), nonalcoholic subjects with cirrhosis (N = 33), and normal controls (N = 31). Muscle strength and endurance were comparable in the alcoholic and nonalcoholic cirrhotic subjects for all variables. Both cirrhotic groups were inferior to normal controls for all variables. The quantity X frequency (Q X F) index reported for the period during peak alcohol consumption correlated with 6 muscle-force variables, accounting for 9-20% of the variance. Alcoholic and nonalcoholic cirrhotic subjects did not differ in Quality of Life Inventory (QOLI) scales. Significant correlations, however, were found for the alcoholic cirrhotic subjects but not for the nonalcoholic cirrhotic subjects between quality-of- life indices and muscle strength and endurance. Muscle weakness is thus differentially associated with quality of life in alcoholic cirrhotic subjects as compared with nonalcoholic subjects with cirrhosis even though level of strength and endurance in the two groups is comparable.

Original languageEnglish (US)
Pages (from-to)499-512
Number of pages14
JournalAmerican Journal of Drug and Alcohol Abuse
Volume24
Issue number3
StatePublished - 1998
Externally publishedYes

Fingerprint

Muscle Strength
Liver Transplantation
Fibrosis
Quality of Life
Isometric Contraction
Muscle Weakness
Alcoholics
Muscle Contraction
Alcohol Drinking
Equipment and Supplies
Muscles

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Psychology

Cite this

Panzak, G., Tarter, R., Murali, S., Switala, J., Lu, S., Maher, B., & Van Thiel, D. H. (1998). Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates. American Journal of Drug and Alcohol Abuse, 24(3), 499-512.

Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates. / Panzak, George; Tarter, Ralph; Murali, Srinivas; Switala, JoAnn; Lu, Sandra; Maher, Brion; Van Thiel, David H.

In: American Journal of Drug and Alcohol Abuse, Vol. 24, No. 3, 1998, p. 499-512.

Research output: Contribution to journalArticle

Panzak, G, Tarter, R, Murali, S, Switala, J, Lu, S, Maher, B & Van Thiel, DH 1998, 'Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates', American Journal of Drug and Alcohol Abuse, vol. 24, no. 3, pp. 499-512.
Panzak, George ; Tarter, Ralph ; Murali, Srinivas ; Switala, JoAnn ; Lu, Sandra ; Maher, Brion ; Van Thiel, David H. / Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates. In: American Journal of Drug and Alcohol Abuse. 1998 ; Vol. 24, No. 3. pp. 499-512.
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