Abstract
Intensity of isometric muscle contractions was measured in alcoholic subjects with cirrhosis (N = 42), nonalcoholic subjects with cirrhosis (N = 33), and normal controls (N = 31). Muscle strength and endurance were comparable in the alcoholic and nonalcoholic cirrhotic subjects for all variables. Both cirrhotic groups were inferior to normal controls for all variables. The quantity X frequency (Q X F) index reported for the period during peak alcohol consumption correlated with 6 muscle-force variables, accounting for 9-20% of the variance. Alcoholic and nonalcoholic cirrhotic subjects did not differ in Quality of Life Inventory (QOLI) scales. Significant correlations, however, were found for the alcoholic cirrhotic subjects but not for the nonalcoholic cirrhotic subjects between quality-of- life indices and muscle strength and endurance. Muscle weakness is thus differentially associated with quality of life in alcoholic cirrhotic subjects as compared with nonalcoholic subjects with cirrhosis even though level of strength and endurance in the two groups is comparable.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 499-512 |
| Number of pages | 14 |
| Journal | American Journal of Drug and Alcohol Abuse |
| Volume | 24 |
| Issue number | 3 |
| State | Published - 1998 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Pharmacology, Toxicology and Pharmaceutics(all)
- Clinical Psychology
Cite this
Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates. / Panzak, George; Tarter, Ralph; Murali, Srinivas; Switala, JoAnn; Lu, Sandra; Maher, Brion; Van Thiel, David H.
In: American Journal of Drug and Alcohol Abuse, Vol. 24, No. 3, 1998, p. 499-512.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Isometric muscle strength in alcoholic and nonalcoholic liver- transplantation candidates
AU - Panzak, George
AU - Tarter, Ralph
AU - Murali, Srinivas
AU - Switala, JoAnn
AU - Lu, Sandra
AU - Maher, Brion
AU - Van Thiel, David H.
PY - 1998
Y1 - 1998
N2 - Intensity of isometric muscle contractions was measured in alcoholic subjects with cirrhosis (N = 42), nonalcoholic subjects with cirrhosis (N = 33), and normal controls (N = 31). Muscle strength and endurance were comparable in the alcoholic and nonalcoholic cirrhotic subjects for all variables. Both cirrhotic groups were inferior to normal controls for all variables. The quantity X frequency (Q X F) index reported for the period during peak alcohol consumption correlated with 6 muscle-force variables, accounting for 9-20% of the variance. Alcoholic and nonalcoholic cirrhotic subjects did not differ in Quality of Life Inventory (QOLI) scales. Significant correlations, however, were found for the alcoholic cirrhotic subjects but not for the nonalcoholic cirrhotic subjects between quality-of- life indices and muscle strength and endurance. Muscle weakness is thus differentially associated with quality of life in alcoholic cirrhotic subjects as compared with nonalcoholic subjects with cirrhosis even though level of strength and endurance in the two groups is comparable.
AB - Intensity of isometric muscle contractions was measured in alcoholic subjects with cirrhosis (N = 42), nonalcoholic subjects with cirrhosis (N = 33), and normal controls (N = 31). Muscle strength and endurance were comparable in the alcoholic and nonalcoholic cirrhotic subjects for all variables. Both cirrhotic groups were inferior to normal controls for all variables. The quantity X frequency (Q X F) index reported for the period during peak alcohol consumption correlated with 6 muscle-force variables, accounting for 9-20% of the variance. Alcoholic and nonalcoholic cirrhotic subjects did not differ in Quality of Life Inventory (QOLI) scales. Significant correlations, however, were found for the alcoholic cirrhotic subjects but not for the nonalcoholic cirrhotic subjects between quality-of- life indices and muscle strength and endurance. Muscle weakness is thus differentially associated with quality of life in alcoholic cirrhotic subjects as compared with nonalcoholic subjects with cirrhosis even though level of strength and endurance in the two groups is comparable.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031667753&partnerID=8YFLogxK
M3 - Article
VL - 24
SP - 499
EP - 512
JO - American Journal of Drug and Alcohol Abuse
JF - American Journal of Drug and Alcohol Abuse
SN - 0095-2990
IS - 3
ER -