Isolation Studies of Allergens from Ragweed Pollen

T. P. King, P. S. Norman

Research output: Contribution to journalArticlepeer-review

Abstract

A highly allergenic protein preparation apparently of 32,000 molecular weight has been isolated from the ragweed pollen extract by ammonium sulfate precipitation followed by chromatography on DEAE cellulose and on Sephadex. A second component of about 10,000 molecular weight was found to be also highly reactive in four out of thirty-two untreated hay fever patients. A cause for the gradual loss of the allergenic activity of ragweed pollen extract on storage is suggested.

Original languageEnglish (US)
Pages (from-to)709-720
Number of pages12
JournalBiochemistry
Volume1
Issue number4
DOIs
StatePublished - Jul 1962

ASJC Scopus subject areas

  • Biochemistry

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