Isolation Studies of Allergens from Ragweed Pollen

T. P. King; P. S. Norman

doi:10.1021/bi00910a027

Isolation Studies of Allergens from Ragweed Pollen

T. P. King, P. S. Norman

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

A highly allergenic protein preparation apparently of 32,000 molecular weight has been isolated from the ragweed pollen extract by ammonium sulfate precipitation followed by chromatography on DEAE cellulose and on Sephadex. A second component of about 10,000 molecular weight was found to be also highly reactive in four out of thirty-two untreated hay fever patients. A cause for the gradual loss of the allergenic activity of ragweed pollen extract on storage is suggested.

Original language	English (US)
Pages (from-to)	709-720
Number of pages	12
Journal	Biochemistry
Volume	1
Issue number	4
DOIs	https://doi.org/10.1021/bi00910a027
State	Published - Jul 1962

ASJC Scopus subject areas

Biochemistry

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title = "Isolation Studies of Allergens from Ragweed Pollen",

abstract = "A highly allergenic protein preparation apparently of 32,000 molecular weight has been isolated from the ragweed pollen extract by ammonium sulfate precipitation followed by chromatography on DEAE cellulose and on Sephadex. A second component of about 10,000 molecular weight was found to be also highly reactive in four out of thirty-two untreated hay fever patients. A cause for the gradual loss of the allergenic activity of ragweed pollen extract on storage is suggested.",

author = "King, {T. P.} and Norman, {P. S.}",

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