Abstract
A highly allergenic protein preparation apparently of 32,000 molecular weight has been isolated from the ragweed pollen extract by ammonium sulfate precipitation followed by chromatography on DEAE cellulose and on Sephadex. A second component of about 10,000 molecular weight was found to be also highly reactive in four out of thirty-two untreated hay fever patients. A cause for the gradual loss of the allergenic activity of ragweed pollen extract on storage is suggested.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 709-720 |
| Number of pages | 12 |
| Journal | Biochemistry® |
| Volume | 1 |
| Issue number | 4 |
| State | Published - 1962 |
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ASJC Scopus subject areas
- Biochemistry
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Isolation studies of allergens from ragweed pollen. / King, T. P.; Norman, Philip S.
In: Biochemistry®, Vol. 1, No. 4, 1962, p. 709-720.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Isolation studies of allergens from ragweed pollen
AU - King, T. P.
AU - Norman, Philip S.
PY - 1962
Y1 - 1962
N2 - A highly allergenic protein preparation apparently of 32,000 molecular weight has been isolated from the ragweed pollen extract by ammonium sulfate precipitation followed by chromatography on DEAE cellulose and on Sephadex. A second component of about 10,000 molecular weight was found to be also highly reactive in four out of thirty-two untreated hay fever patients. A cause for the gradual loss of the allergenic activity of ragweed pollen extract on storage is suggested.
AB - A highly allergenic protein preparation apparently of 32,000 molecular weight has been isolated from the ragweed pollen extract by ammonium sulfate precipitation followed by chromatography on DEAE cellulose and on Sephadex. A second component of about 10,000 molecular weight was found to be also highly reactive in four out of thirty-two untreated hay fever patients. A cause for the gradual loss of the allergenic activity of ragweed pollen extract on storage is suggested.
UR - http://www.scopus.com/inward/record.url?scp=0001531307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0001531307&partnerID=8YFLogxK
M3 - Article
C2 - 14456133
AN - SCOPUS:0001531307
VL - 1
SP - 709
EP - 720
JO - Biochemistry
JF - Biochemistry
SN - 0006-2960
IS - 4
ER -