TY - JOUR
T1 - Isolation of monochromosomal hybrids following fusion of human diploid fibroblast-derived microcells with mouse A9 cells
AU - Ning, Yi
AU - Lovell, M.
AU - Taylor, L.
AU - Pereira-Smith, O. M.
PY - 1992
Y1 - 1992
N2 - Rodent x human hybrids containing single hitman chromosomes are valuable tools in the study of human genetics. Using a retrovirus carrying the neomycin gene, we generated a neomycin-resistant (ncor) pool of human diploid fibroblasts. Following fusion of microcells prepared from this pool to mouse A9 cells, we obtained four ncor hybrids containing a single human chromosome 2, 3, 5, or 15.
AB - Rodent x human hybrids containing single hitman chromosomes are valuable tools in the study of human genetics. Using a retrovirus carrying the neomycin gene, we generated a neomycin-resistant (ncor) pool of human diploid fibroblasts. Following fusion of microcells prepared from this pool to mouse A9 cells, we obtained four ncor hybrids containing a single human chromosome 2, 3, 5, or 15.
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U2 - 10.1159/000133300
DO - 10.1159/000133300
M3 - Article
C2 - 1582264
AN - SCOPUS:0026523750
SN - 0301-0171
VL - 60
SP - 79
EP - 80
JO - Cytogenetics and cell genetics
JF - Cytogenetics and cell genetics
IS - 1
ER -