Isolation of inactive and G protein-resistant adenylyl cyclase mutants using random mutagenesis

Medicine & Life Sciences

• Adenylyl Cyclases 100%
• GTP-Binding Proteins 97%
• Mutagenesis 96%
• Enzymes 53%
• Formyl Peptide Receptor 47%
• Guanosine 5'-O-(3-Thiotriphosphate) 46%
• Dictyostelium 42%
• Null Lymphocytes 41%
• Catalysis 39%
• Loss of Function Mutation 37%
• Missense Mutation 33%
• Cell Membrane 23%
• Mutation 18%
• Proteins 12%

Chemical Compounds

• Mutation 83%
• Chemoattractant 48%
• Guanosine 35%
• Catalysis 21%
• Substitution Reaction 20%
• Plasma 20%
• Protein 13%