@article{7789454b4d374f2680e504b7df74d88c,
title = "Isolation of a yeast artificial chromosome clone that spans the (12;16) translocation breakpoint characteristic of myxoid liposarcoma",
abstract = "Cytogenetic analysis of liposarcomas has demonstrated that translocation (12;16) (q13.3;p11.2) is characteristic of the myxoid subtype of this adipose tissue tumor. Our previous results suggested that the GLI gene is close to the translocation breakpoint on chromosome 12. We now describe a yeast artificial chromosome (YAC) that contains GLI and spans the chromosome 12 region involved in the t(12;16) breakpoint. This clone will permit rapid definition of the genetic region surrounding the breakpoint and allow isolation of the gene presumably affected by the translocation.",
author = "Gemmill, {Robert M.} and Mendez, {Michael J.} and Dougherty, {Cynthia M.} and Sylvie Paulien and Martha Liao and Deanna Mitchell and Jankowski, {Sheryl A.} and Trent, {Jeffrey M.} and Carol Berger and Sandberg, {Avery A.} and Meltzer, {Paul S.}",
note = "Funding Information: The authors thank Drs. Denis Le Paslier and Daniel Cohen for providing the C.E.P.H. human YAC library and Dr. Bert Vogelstein for providing the GLI probes. This study was supported in part by Program Project grant No. CA-41183 and by Grant No. CA-56725 to P. S. M. from the National Institutes of Health. In addition, this work was supported by a grant from the Colorado Cancer League to R. M. G., by a grant from Amoco Technology, Naperville, IL to P. S. M. and by a grant from the American Foundation for AIDS Research to M. L. The expert technical assistance of Ann Burgess, Tom Dennis, and Efang Li is gratefully acknowledged.",
year = "1992",
month = sep,
doi = "10.1016/0165-4608(92)90257-9",
language = "English (US)",
volume = "62",
pages = "166--170",
journal = "Cancer Genetics and Cytogenetics",
issn = "0165-4608",
publisher = "Elsevier Inc.",
number = "2",
}