Isolation and long-term cell culture of epithelial-like cells from rat liver

G. M. Williams; Elizabeth K. Weisburger; J. H. Weisburger

doi:10.1016/0014-4827(71)90316-8

Isolation and long-term cell culture of epithelial-like cells from rat liver

G. M. Williams, Elizabeth K. Weisburger, J. H. Weisburger

School of Medicine

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174 Scopus citations

Abstract

Epithelial-like cells from livers of 10-day-old rats were separated from fibroblast-like cells on the basis of differential attachment to a culture surface. After further elimination of persisting fibroblast-like cells from the cultures of epithelial-like cells, lines of the latter cell type were initiated and these maintained their morphology for up to nine months of continuous culture and displayed no tumorigenicity upon injection into syngeneic hosts.

Original language	English (US)
Pages (from-to)	106-112
Number of pages	7
Journal	Experimental cell research
Volume	69
Issue number	1
DOIs	https://doi.org/10.1016/0014-4827(71)90316-8
State	Published - Nov 1971

ASJC Scopus subject areas

Cell Biology

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10.1016/0014-4827(71)90316-8

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title = "Isolation and long-term cell culture of epithelial-like cells from rat liver",

abstract = "Epithelial-like cells from livers of 10-day-old rats were separated from fibroblast-like cells on the basis of differential attachment to a culture surface. After further elimination of persisting fibroblast-like cells from the cultures of epithelial-like cells, lines of the latter cell type were initiated and these maintained their morphology for up to nine months of continuous culture and displayed no tumorigenicity upon injection into syngeneic hosts.",

author = "Williams, {G. M.} and Weisburger, {Elizabeth K.} and Weisburger, {J. H.}",

year = "1971",

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AU - Weisburger, Elizabeth K.

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AB - Epithelial-like cells from livers of 10-day-old rats were separated from fibroblast-like cells on the basis of differential attachment to a culture surface. After further elimination of persisting fibroblast-like cells from the cultures of epithelial-like cells, lines of the latter cell type were initiated and these maintained their morphology for up to nine months of continuous culture and displayed no tumorigenicity upon injection into syngeneic hosts.

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Isolation and long-term cell culture of epithelial-like cells from rat liver

Abstract

ASJC Scopus subject areas

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