Abstract
We used a near full-length human ornithine δ-aminotransferase cDNA, huOAT6, as a probe under low stringency hybridization conditions to identify a new autosomal ornithine δ-aminotransferase-related sequence (OATL3). Cloning and characterization of this sequence reveal it to be a partial nonprocessed pseudogene corresponding to exon 3 and flanking intronic sequences of the ornithine δ-aminotransferase structural gene. Using somatic cell hybrids and fluorescence in situ hybridization, we mapped OATL3 to 10q26, adjacent to the ornithine δ-aminotransferase structural gene locus.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 510-513 |
| Number of pages | 4 |
| Journal | Genomics |
| Volume | 17 |
| Issue number | 2 |
| DOIs | |
| State | Published - Aug 1993 |
ASJC Scopus subject areas
- Genetics
Fingerprint Dive into the research topics of 'Isolation and characterization of an ornithine aminotransferase-related sequence (oatl3) mapping to 10q26'. Together they form a unique fingerprint.
Cite this
Geraghty, M. T., Kearns, W. G., Pearson, P. L., & Valle, D. (1993). Isolation and characterization of an ornithine aminotransferase-related sequence (oatl3) mapping to 10q26. Genomics, 17(2), 510-513. https://doi.org/10.1006/geno.1993.1358