Isolated Whipple disease of the brain resembling a tumour

James L. Frazier, Alfredo Quinones-Hinojosa

Research output: Contribution to journalArticle

Abstract

Introduction: Isolated Whipple disease of the central nervous system is a rare occurrence. Migratory arthralgias and gastrointestinal problems, including malabsorption, abdominal pain, diarrhea, and weight loss, are common presenting symptoms. Discussion: For those patients with systemic signs and symptoms of Whipple disease, 6% to 43% will have clinically manifested CNS involvement that may include alterations in personality, ataxia, and dementia. We report our experience with a patient, who was successfully treated for Whipple disease 12 years prior to presentation and had a magnetic resonance image of the brain that revealed two solitary lesions resembling a tumor upon presentation.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalActa Neurochirurgica
Volume151
Issue number2
DOIs
StatePublished - Feb 2009

Fingerprint

Whipple Disease
Brain
Neoplasms
Arthralgia
Ataxia
Abdominal Pain
Signs and Symptoms
Personality
Dementia
Weight Loss
Diarrhea
Magnetic Resonance Spectroscopy
Central Nervous System

Keywords

  • Brain
  • Central nervous system
  • Tumour
  • Whipple disease
  • Whipple's bacilli

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Isolated Whipple disease of the brain resembling a tumour. / Frazier, James L.; Quinones-Hinojosa, Alfredo.

In: Acta Neurochirurgica, Vol. 151, No. 2, 02.2009, p. 173-175.

Research output: Contribution to journalArticle

Frazier, James L. ; Quinones-Hinojosa, Alfredo. / Isolated Whipple disease of the brain resembling a tumour. In: Acta Neurochirurgica. 2009 ; Vol. 151, No. 2. pp. 173-175.
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