Isolated aneurysms of the spinal circulation: a systematic review of the literature

Safwan Alomari, Risheng Xu, Judy Huang, Rafael Tamargo, Ali Bydon

Research output: Contribution to journalReview articlepeer-review


Aneurysms arising in the spinal circulation are rare and underreported. The objective of this study was to systematically review the English literature on different aspects of isolated spinal aneurysms using the PubMed, Ovid MEDLINE, and Google Scholar databases. Eighty-two papers reporting 107 individual patient cases were included. Most isolated spinal aneurysms have a fusiform morphology, and are most commonly found in the anterior spinal artery at the thoracic or cervical levels. Subarachnoid hemorrhage is the most common form of presentation, and sudden onset back pain is the most common initial symptom. The diagnosis of spinal aneurysms requires a high degree of clinical suspicion. Because of their small size, they can be missed on CT/MR angiography and spinal angiogram may be employed. Treatment of spinal aneurysms should be individualized on a case-by-case basis. Conservative management can be a valid option in spinal aneurysms where the risk of treatment is high. Surgical or endovascular intervention may be indicated in cases of significant or progressive neurologic decline due aneurysmal mass effect, or progressive growth of the aneurysm despite conservative treatment.

Original languageEnglish (US)
Pages (from-to)989-1008
Number of pages20
JournalNeurosurgical Review
Issue number2
StatePublished - Apr 2022


  • Aneurysms
  • Spinal circulation
  • Systematic review of the literature

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


Dive into the research topics of 'Isolated aneurysms of the spinal circulation: a systematic review of the literature'. Together they form a unique fingerprint.

Cite this