Ischemic ventricular fibrillation: The importance of being spontaneous

Pamela Ouyang, Jeffrey A Brinker, Bernadine H. Bulkley, Bodh I. Jugdutt, Paul J. Varghese

Research output: Contribution to journalArticle

Abstract

Although the energy level required to defibrillate normal myocardium is low and constant, as determined from studies of induced ventricular fibrillation, little is known of the specific energy requirements in regionally ischemic hearts for spontaneous or induced ventricular fibrillation. In this study the lowest energy threshold for defibrillation was determined in 10 open chest dogs with reversible 10 minute coronary occlusions at various sites for each of 44 events of ventricular fibrillation, using apical and superior vena caval electrodes with a generator providing variable output of 1 to 30 watt seconds. The ischemic mass, quantitated from postmortem angiographic and planimetric data, was 52 ± 9 percent (mean ± standard deviation) of the left ventricle in dogs with induced ventricular fibrillation (Group I), 52 ± 12 percent in dogs with spontaneous ventricular fibrillation after occlusion (Group II) and 54 ± 9 percent in dogs with spontaneous ventricular fibrillation after reperfusion (Group III). Defibrillation thresholds in watt seconds were 9 ± 7 in Group I (n = 12), 19 ± 10 in Group II (n = 13) and 18 ± 10 in Group III (n = 19). (Group I versus Groups II and III, probability [p]

Original languageEnglish (US)
Pages (from-to)455-459
Number of pages5
JournalThe American Journal of Cardiology
Volume48
Issue number3
DOIs
StatePublished - 1981

Fingerprint

Ventricular Fibrillation
Dogs
Venae Cavae
Coronary Occlusion
Reperfusion
Heart Ventricles
Myocardium
Electrodes
Thorax

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Ischemic ventricular fibrillation : The importance of being spontaneous. / Ouyang, Pamela; Brinker, Jeffrey A; Bulkley, Bernadine H.; Jugdutt, Bodh I.; Varghese, Paul J.

In: The American Journal of Cardiology, Vol. 48, No. 3, 1981, p. 455-459.

Research output: Contribution to journalArticle

Ouyang, Pamela ; Brinker, Jeffrey A ; Bulkley, Bernadine H. ; Jugdutt, Bodh I. ; Varghese, Paul J. / Ischemic ventricular fibrillation : The importance of being spontaneous. In: The American Journal of Cardiology. 1981 ; Vol. 48, No. 3. pp. 455-459.
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