Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility

K. Datta, P. Rhee, E. Byrnes, G. Garcia-Effron, D. S. Perlin, J. F. Staab, K. A. Marr

Research output: Contribution to journalArticle

Abstract

Isavuconazole is an extended-spectrum triazole with in vitro activity against a wide variety of fungal pathogens. Clinical isolates of molds Aspergillus lentulus and Neosartorya udagawae and yeast Cryptococcus gattii VGII (implicated in the outbreak in the Pacific Northwest, North America) exhibit reduced susceptibilities to several azoles but higher susceptibilities to isavuconazole.

Original languageEnglish (US)
Pages (from-to)3090-3093
Number of pages4
JournalJournal of clinical microbiology
Volume51
Issue number9
DOIs
StatePublished - Sep 1 2013

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ASJC Scopus subject areas

  • Microbiology (medical)

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