Is thromboelastography (TEG)-based resuscitation better than empirical 1:1 transfusion?

Isaac W. Howley, Elliott R. Haut, Lenwoth Jacobs, Jonathan J. Morrison, Thomas M. Scalea

Research output: Contribution to journalArticlepeer-review

Abstract

Thomboelastography (TEG) is a whole blood measure of coagulation which was originally described in the 1950s. However, it has only been in the last few decades that assays have become accessible and viable as a point-of-care test. Following the observation that hemorrhagic shock is associated with an intrinsic coagulopathy, TEG has been used as a method of diagnosing specific coagulation defects in order to direct individualized blood products resuscitation. An alternative transfusion strategy is the administration of fixed ratio products, a paradigm borne out of military experience. It is unknown which strategy is superior and this topic was debated at the 36th Annual Point/Counterpoint Acute Care Surgery Conference. The following article summarizes the discussants points of view along with a summary of the evidence.Level of Evidence Level III.

Original languageEnglish (US)
Article numbere000140
JournalTrauma Surgery and Acute Care Open
Volume3
Issue number1
DOIs
StatePublished - Jan 2018

ASJC Scopus subject areas

  • Surgery
  • Critical Care and Intensive Care Medicine

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