Is there an optimal respiratory reference position for self-navigated whole-heart coronary MR angiography?

Davide Piccini, Gabriele Bonanno, Giulia Ginami, Arne Littmann, Michael O. Zenge, Matthias Stuber

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Purpose To test the direct influence of the reference respiratory position on image quality for self-navigated whole-heart coronary MRI. Methods Self-navigated whole-heart coronary MRI was performed in 11 healthy adult subjects. Respiratory motion was compensated for by using three different respiratory reference positions of the heart: end-inspiratory, end-expiratory, and the mean of the entire respiratory excursion. All datasets were reconstructed without motion compensation for comparison. Image quality was assessed in all reconstructions using signal-to-noise ratio (SNR) and contrst-to-noise ratio (CNR) measurements, as well as percentage vessel sharpness and visible length of the coronary arteries. Results While SNR and CNR remained close to constant in all reconstructions, a clear and significant improvement in vessel sharpness was identified in all motion corrected datasets with respect to their uncorrected counterpart (e.g., percentage sharpness of the proximal right coronary artery (RCA): 61.6 ± 8.2% for end-inspiration, 64.1 ± 10.7% for end-expiration, and 63.3 ± 7.0% for the mean respiratory position versus 55.0 ± 10.4 for the uncorrected datasets; P < 0.05). Among all motion corrected reconstructions, the use of an end-expiratory reference position most consistently provided the highest image quality. In particular, some of the improvements in vessel sharpness and length measured for end-expiration were statistically significant with respect to the reconstructions performed at end-inspiration (e.g., percentage sharpness of the proximal left anterior descending coronary: 58.2 ± 7.4% versus 55.8 ± 8.4%; P < 0.05; and visible length of the RCA: 125.7 ± 25.9 mm versus 114.4 ± 27.4 mm; P < 0.05). Conclusion The use of end-expiration as a reference position for respiratory motion correction in free-breathing self-navigated whole heart coronary MRA significantly improves image quality. J. Magn. Reson. Imaging 2016;43:426-433.

Original languageEnglish (US)
Pages (from-to)426-433
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Issue number2
StatePublished - Feb 1 2016


  • coronary MRA
  • free-breathing
  • reference position
  • respiratory motion
  • self-navigation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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