Is the OSA-18 predictive of obstructive sleep apnea: Comparison to polysomnography

Stacey L. Ishman, Christina J. Yang, Aliza P. Cohen, James R. Benke, Jareen K. Meinzen-Derr, Rebecca M. Anderson, Marie E. Madden, Meredith E. Tabangin

Research output: Contribution to journalArticle

Abstract

Objectives/Hypothesis To examine the ability of the OSA-18 to predict Obstructive Sleep Apnea (OSA) in a racially diverse population when compared to overnight polysomnography (PSG). Study Design Cross-sectional retrospective. Methods Children 2 to 12 years of age diagnosed with OSA who were treated at a tertiary care institution between 2008 and 2013 and had complete PSG and OSA-18 data were included. We performed logistic regression with OSA as the dependent variable and the OSA-18 total symptom score (TSS), age, gender, race, asthma, and body mass index (BMI) as independent variables. Results Seventy-nine children (32 females) were included (mean age 5.2 ± 2.4 years). The positive predictive value (PPV) was greater than 90 for an obstructive apnea-hypopnea index (oAHI) ≥ 1. The PPV and specificity were higher for white than for nonwhite children; however, sensitivity and negative predictive value (NPV) of OSA-18 TSS were low for mild, moderate, and severe OSA regardless of race. Age, race, and BMI were not significantly associated with oAHI. Conclusions This study, conducted in a racially diverse cohort, examined the ability of the OSA-18 to predict OSA when compared to PSG - the gold standard - and found that sensitivity and NPV were extremely low for both white and nonwhite children. This suggests that the OSA-18 is not sufficiently sensitive to detect OSA nor sufficiently specific to determine the absence of OSA. The OSA-18 should be used as a quality-of-life indicator and is not a reliable substitute for PSG.

Original languageEnglish (US)
Pages (from-to)1491-1495
Number of pages5
JournalLaryngoscope
Volume125
Issue number6
DOIs
StatePublished - Jun 1 2015

Keywords

  • OSA-18
  • obstructive sleep apnea
  • polysomnography
  • quality of life

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Ishman, S. L., Yang, C. J., Cohen, A. P., Benke, J. R., Meinzen-Derr, J. K., Anderson, R. M., Madden, M. E., & Tabangin, M. E. (2015). Is the OSA-18 predictive of obstructive sleep apnea: Comparison to polysomnography. Laryngoscope, 125(6), 1491-1495. https://doi.org/10.1002/lary.25098