Is longitudinal pulse pressure a better predictor of 24-hour urinary albumin excretion than other indices of blood pressure?

S. Morteza Farasat, Carolina Valdes, Veena Shetty, Denis C. Muller, Josephine M. Egan, E. Jeffrey Metter, Luigi Ferrucci, Samer S. Najjar

Research output: Contribution to journalArticlepeer-review

Abstract

The strong relationship between urinary albumin excretion (UAE) and pulse pressure (PP) in cross-sectional studies suggests that pressure pulsatility may contribute to renal microvascular injury. The longitudinal relationships between UAE and the various indices of blood pressure (BP) are not well studied. We compared the associations of UAE with the longitudinal exposure to PP and systolic, diastolic, and mean BPs. UAE was measured from 24-hour urine collections in 450 community-dwelling subjects (age: 57±15 years, 53% women, all with UAE

Original languageEnglish (US)
Pages (from-to)415-421
Number of pages7
JournalHypertension
Volume55
Issue number2
DOIs
StatePublished - Feb 2010
Externally publishedYes

Keywords

  • Albuminuria
  • Longitudinal studies
  • Microvascular
  • Pulse pressure
  • Renal function

ASJC Scopus subject areas

  • Internal Medicine

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