Is longitudinal pulse pressure a better predictor of 24-hour urinary albumin excretion than other indices of blood pressure?

S. Morteza Farasat; Carolina Valdes; Veena Shetty; Denis C. Muller; Josephine M. Egan; E. Jeffrey Metter; Luigi Ferrucci; Samer S. Najjar

doi:10.1161/HYPERTENSIONAHA.109.135087

Is longitudinal pulse pressure a better predictor of 24-hour urinary albumin excretion than other indices of blood pressure?

S. Morteza Farasat, Carolina Valdes, Veena Shetty, Denis C. Muller, Josephine M. Egan, E. Jeffrey Metter, Luigi Ferrucci, Samer S. Najjar

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The strong relationship between urinary albumin excretion (UAE) and pulse pressure (PP) in cross-sectional studies suggests that pressure pulsatility may contribute to renal microvascular injury. The longitudinal relationships between UAE and the various indices of blood pressure (BP) are not well studied. We compared the associations of UAE with the longitudinal exposure to PP and systolic, diastolic, and mean BPs. UAE was measured from 24-hour urine collections in 450 community-dwelling subjects (age: 57±15 years, 53% women, all with UAE

Original language	English (US)
Pages (from-to)	415-421
Number of pages	7
Journal	Hypertension
Volume	55
Issue number	2
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.109.135087
State	Published - Feb 2010
Externally published	Yes

Keywords

Albuminuria
Longitudinal studies
Microvascular
Pulse pressure
Renal function

ASJC Scopus subject areas

Internal Medicine

Access to Document

10.1161/HYPERTENSIONAHA.109.135087

Cite this

@article{640365fa07fb4eb7b99fb796b57642cb,

title = "Is longitudinal pulse pressure a better predictor of 24-hour urinary albumin excretion than other indices of blood pressure?",

abstract = "The strong relationship between urinary albumin excretion (UAE) and pulse pressure (PP) in cross-sectional studies suggests that pressure pulsatility may contribute to renal microvascular injury. The longitudinal relationships between UAE and the various indices of blood pressure (BP) are not well studied. We compared the associations of UAE with the longitudinal exposure to PP and systolic, diastolic, and mean BPs. UAE was measured from 24-hour urine collections in 450 community-dwelling subjects (age: 57±15 years, 53% women, all with UAE ",

keywords = "Albuminuria, Longitudinal studies, Microvascular, Pulse pressure, Renal function",

author = "Farasat, {S. Morteza} and Carolina Valdes and Veena Shetty and Muller, {Denis C.} and Egan, {Josephine M.} and Metter, {E. Jeffrey} and Luigi Ferrucci and Najjar, {Samer S.}",

year = "2010",

month = feb,

doi = "10.1161/HYPERTENSIONAHA.109.135087",

language = "English (US)",

volume = "55",

pages = "415--421",

journal = "Hypertension",

issn = "0194-911X",