Is it time to advance the chemoprevention of environmental carcinogenesis with microdosing trials?

Research output: Contribution to journalReview articlepeer-review

Abstract

This perspective on Jubert et al. (beginning on page [1015] in this issue of the journal) discusses the use of microdosing with environmental carcinogens to accelerate the evaluation and optimization of chemopreventive interventions. The need for chemoprevention of environmental carcinogenesis is considered, as are the structure of microdosing, or phase 0, trials, technologies required to conduct microdose studies in this context, and ethical concerns. We also reflect on what microdosing studies have taught us to date.

Original languageEnglish (US)
Pages (from-to)1003-1007
Number of pages5
JournalCancer Prevention Research
Volume2
Issue number12
DOIs
StatePublished - Dec 2009

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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