Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

P. W.J. Harvey; R. G. Bell; M. C. Nesheim

doi:10.1128/iai.50.3.932-934.1985

Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

P. W.J. Harvey, R. G. Bell, M. C. Nesheim

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.

Original language	English (US)
Pages (from-to)	932-934
Number of pages	3
Journal	Infection and immunity
Volume	50
Issue number	3
DOIs	https://doi.org/10.1128/iai.50.3.932-934.1985
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

Access to Document

10.1128/iai.50.3.932-934.1985

Cite this

@article{c19cc357ac634456848b7951f0a25632,

title = "Iron deficiency protects inbred mice against infection with Plasmodium chabaudi",

abstract = "Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.",

author = "Harvey, {P. W.J.} and Bell, {R. G.} and Nesheim, {M. C.}",

year = "1985",

doi = "10.1128/iai.50.3.932-934.1985",

language = "English (US)",

volume = "50",

pages = "932--934",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "3",

}

TY - JOUR

T1 - Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

AU - Harvey, P. W.J.

AU - Bell, R. G.

AU - Nesheim, M. C.

PY - 1985

Y1 - 1985

N2 - Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.

AB - Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.

UR - http://www.scopus.com/inward/record.url?scp=0022410841&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022410841&partnerID=8YFLogxK

U2 - 10.1128/iai.50.3.932-934.1985

DO - 10.1128/iai.50.3.932-934.1985

M3 - Article

C2 - 4066038

AN - SCOPUS:0022410841

VL - 50

SP - 932

EP - 934

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 3

ER -

Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this