Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

P. W.J. Harvey; R. G. Bell; M. C. Nesheim

doi:10.1128/iai.50.3.932-934.1985

Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

P. W.J. Harvey, R. G. Bell, M. C. Nesheim

Research output: Contribution to journal › Article › peer-review

Abstract

Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.

Original language	English (US)
Pages (from-to)	932-934
Number of pages	3
Journal	Infection and immunity
Volume	50
Issue number	3
DOIs	https://doi.org/10.1128/iai.50.3.932-934.1985
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Microbiology
Immunology
Infectious Diseases

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10.1128/iai.50.3.932-934.1985

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title = "Iron deficiency protects inbred mice against infection with Plasmodium chabaudi",

abstract = "Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.",

author = "Harvey, {P. W.J.} and Bell, {R. G.} and Nesheim, {M. C.}",

year = "1985",

doi = "10.1128/iai.50.3.932-934.1985",

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AU - Bell, R. G.

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AB - Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.

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Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

Abstract

ASJC Scopus subject areas

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