Iron deficiency protects inbred mice against infection with Plasmodium chabaudi

P. W.J. Harvey, R. G. Bell, M. C. Nesheim

Research output: Contribution to journalArticle

Abstract

Plasmodium chabaudi infections of NFR/N mice made anemic by dietary iron deficiency produced mortalities of 25% (male) and 7% (female) compared with 100% in iron-sufficient controls. When iron-deficient mice convalescing from the primary infection were returned to the normal diet, 100% experienced recrudescent parasitemia. No recrudescence occurred in mice maintained on the iron-deficient diet.

Original languageEnglish (US)
Pages (from-to)932-934
Number of pages3
JournalInfection and immunity
Volume50
Issue number3
DOIs
StatePublished - 1985

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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