Ion-channel assay technologies: Quo vadis?

Jia Xu, Xiaobo Wang, Brooks Ensign, Min Li, Lei Wu, Antonio Guia, Junquan Xu

Research output: Contribution to journalReview articlepeer-review

Abstract

Although many existing methods are used to study the functions of ion channels and to screen lead compounds for important ion-channel targets, new technologies are being developed for improved performance. It is important to identify the advantages and disadvantages of each technology. In this review, we segment the ion-channel assay market according to distinguishable applications, and compare the needs of each market segment with the capabilities of different technologies in terms of multiple assay attributes. We further discuss the future directions in the development of ion-channel assays.

Original languageEnglish (US)
Pages (from-to)1278-1287
Number of pages10
JournalDrug Discovery Today
Volume6
Issue number24
DOIs
StatePublished - Dec 15 2001

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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