Iodination of terminal alkynes using KI/CuSO 4 – A facile method with potential for radio-iodination

Trevor Ferris, Laurence Carroll, Ronnie C. Mease, Alan C. Spivey, Eric O. Aboagye

Research output: Contribution to journalArticlepeer-review

Abstract

Herein, we report an efficient new method for the iodination of terminal alkynes using stoichiometric KI and CuSO 4 in a mix of acetonitrile and acetate buffer that holds promise for further development into a method for radio-iodination.

Original languageEnglish (US)
Pages (from-to)936-939
Number of pages4
JournalTetrahedron Letters
Volume60
Issue number13
DOIs
StatePublished - Mar 28 2019

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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