Involvement of thymus in immune response of rabbits to somatic polysaccharides of gram-negative bacteria

Maurice Landy; Ronald P. Sanderson; Michael T. Bernstein; Edwin M. Lerner

doi:10.1126/science.147.3665.1591

Involvement of thymus in immune response of rabbits to somatic polysaccharides of gram-negative bacteria

Maurice Landy, Ronald P. Sanderson, Michael T. Bernstein, Edwin M. Lerner

Research output: Contribution to journal › Article › peer-review

Abstract

Plaque-forming cells elaborating antibody specific for Salmonella enteritidis somatic antigen have been demonstrated in the thymus of rabbits 5 days after a single systemic injection of a minute amount of this bacterial polysaccharide. A marked decrease in organ weight and loss of thymic cellularity was also seen, and was most pronounced at the time when antibody-forming cells made their appearance.

Original language	English (US)
Pages (from-to)	1591-1592
Number of pages	2
Journal	Science
Volume	147
Issue number	3665
DOIs	https://doi.org/10.1126/science.147.3665.1591
State	Published - 1965
Externally published	Yes

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title = "Involvement of thymus in immune response of rabbits to somatic polysaccharides of gram-negative bacteria",

abstract = "Plaque-forming cells elaborating antibody specific for Salmonella enteritidis somatic antigen have been demonstrated in the thymus of rabbits 5 days after a single systemic injection of a minute amount of this bacterial polysaccharide. A marked decrease in organ weight and loss of thymic cellularity was also seen, and was most pronounced at the time when antibody-forming cells made their appearance.",

author = "Maurice Landy and Sanderson, {Ronald P.} and Bernstein, {Michael T.} and Lerner, {Edwin M.}",

year = "1965",

doi = "10.1126/science.147.3665.1591",

language = "English (US)",

volume = "147",

pages = "1591--1592",

journal = "Science",

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publisher = "American Association for the Advancement of Science",

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T1 - Involvement of thymus in immune response of rabbits to somatic polysaccharides of gram-negative bacteria

AU - Landy, Maurice

AU - Sanderson, Ronald P.

AU - Bernstein, Michael T.

AU - Lerner, Edwin M.

PY - 1965

Y1 - 1965

N2 - Plaque-forming cells elaborating antibody specific for Salmonella enteritidis somatic antigen have been demonstrated in the thymus of rabbits 5 days after a single systemic injection of a minute amount of this bacterial polysaccharide. A marked decrease in organ weight and loss of thymic cellularity was also seen, and was most pronounced at the time when antibody-forming cells made their appearance.

AB - Plaque-forming cells elaborating antibody specific for Salmonella enteritidis somatic antigen have been demonstrated in the thymus of rabbits 5 days after a single systemic injection of a minute amount of this bacterial polysaccharide. A marked decrease in organ weight and loss of thymic cellularity was also seen, and was most pronounced at the time when antibody-forming cells made their appearance.

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Involvement of thymus in immune response of rabbits to somatic polysaccharides of gram-negative bacteria

Abstract

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