Abstract
Infantile myofibromatosis is a rare disorder of infancy that can provoke osteolytic lesions. A 15-day-old infant presented with three round, firm lesions located on the forehead, shoulder, and back. Excisional biopsy of the forehead lesion revealed that the tumor was composed of spindle cells resembling normal smooth muscle arranged in short fascicles. Immunohistochemical staining was positive for vimentin and actin. Five months later, the child presented with three new lesions, including one in the superolateral aspect of the left orbit. It is important to recognize the multicentric form of infantile myofibromatosis because, despite its aggressive clinical presentation, the disease is benign and usually does not require extensive surgery or chemotherapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 252-254 |
| Number of pages | 3 |
| Journal | Ophthalmic Plastic and Reconstructive Surgery |
| Volume | 20 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 2004 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
- Surgery
Cite this
Involvement of the bony orbit in infantile myofibromatosis. / Cruz, Antonio Augusto V; Maia, Elizabeth M.; Burmamm, Tiana G.; Perez, Luiz C.; Santos, Andreia N.; Valera, Elvis T.; Tone, Luis G.
In: Ophthalmic Plastic and Reconstructive Surgery, Vol. 20, No. 3, 05.2004, p. 252-254.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Involvement of the bony orbit in infantile myofibromatosis
AU - Cruz, Antonio Augusto V
AU - Maia, Elizabeth M.
AU - Burmamm, Tiana G.
AU - Perez, Luiz C.
AU - Santos, Andreia N.
AU - Valera, Elvis T.
AU - Tone, Luis G.
PY - 2004/5
Y1 - 2004/5
N2 - Infantile myofibromatosis is a rare disorder of infancy that can provoke osteolytic lesions. A 15-day-old infant presented with three round, firm lesions located on the forehead, shoulder, and back. Excisional biopsy of the forehead lesion revealed that the tumor was composed of spindle cells resembling normal smooth muscle arranged in short fascicles. Immunohistochemical staining was positive for vimentin and actin. Five months later, the child presented with three new lesions, including one in the superolateral aspect of the left orbit. It is important to recognize the multicentric form of infantile myofibromatosis because, despite its aggressive clinical presentation, the disease is benign and usually does not require extensive surgery or chemotherapy.
AB - Infantile myofibromatosis is a rare disorder of infancy that can provoke osteolytic lesions. A 15-day-old infant presented with three round, firm lesions located on the forehead, shoulder, and back. Excisional biopsy of the forehead lesion revealed that the tumor was composed of spindle cells resembling normal smooth muscle arranged in short fascicles. Immunohistochemical staining was positive for vimentin and actin. Five months later, the child presented with three new lesions, including one in the superolateral aspect of the left orbit. It is important to recognize the multicentric form of infantile myofibromatosis because, despite its aggressive clinical presentation, the disease is benign and usually does not require extensive surgery or chemotherapy.
UR - http://www.scopus.com/inward/record.url?scp=2542422646&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2542422646&partnerID=8YFLogxK
U2 - 10.1097/01.IOP.0000123501.30336.2C
DO - 10.1097/01.IOP.0000123501.30336.2C
M3 - Article
VL - 20
SP - 252
EP - 254
JO - Ophthalmic Plastic and Reconstructive Surgery
JF - Ophthalmic Plastic and Reconstructive Surgery
SN - 0740-9303
IS - 3
ER -