Involvement of PCH family proteins in cytokinesis and actin distribution

John Lippincott, Rong Li

Research output: Contribution to journalArticle

Abstract

Pombe Cdc15 homology (PCH) proteins constitute an extensive protein family whose members have been found in diverse eukaryotic organisms. These proteins are characterized by the presence of several conserved sequence and structural motifs. Recent studies in yeast and mammalian cultured cells have implicated these proteins in actin-based processes, in particular, cytokinesis. Here we review the recent findings on the in vivo localization, function, and binding partners of PCH family members. We also provide new microscopy data regarding the in vivo dynamics of a budding yeast PCH protein involved in cytokinesis. (C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalMicroscopy Research and Technique
Volume49
Issue number2
DOIs
StatePublished - Apr 15 2000
Externally publishedYes

Fingerprint

Cytokinesis
cytokinesis
homology
actin
Actins
proteins
Proteins
yeast
Yeast
yeasts
Saccharomycetales
conserved sequences
Conserved Sequence
organisms
cultured cells
Microscopy
Cultured Cells
microscopy
Microscopic examination
Yeasts

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Anatomy
  • Instrumentation

Cite this

Involvement of PCH family proteins in cytokinesis and actin distribution. / Lippincott, John; Li, Rong.

In: Microscopy Research and Technique, Vol. 49, No. 2, 15.04.2000, p. 168-172.

Research output: Contribution to journalArticle

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