Invited commentary: Composite outcomes as an attempt to escape from selection bias and related paradoxes

Miguel A. Hernán, Enrique F. Schisterman, Sonia Hernández-Díaz

Research output: Contribution to journalArticle

Abstract

This commentary reviews the recent history of explanations to crossover paradoxes such as the birth weight and gestational age paradoxes, with a special emphasis on the current proposal by Kramer et al. in this issue of the Journal (Am J Epidemiol. 2014;179(3):361-367). We contend that the causal structure of these paradoxes is essentially identical to that of several well-known selection biases. We then consider the pros and cons of using composite outcomes to circumvent these selection biases.

Original languageEnglish (US)
Pages (from-to)368-370
Number of pages3
JournalAmerican Journal of Epidemiology
Volume179
Issue number3
DOIs
StatePublished - Feb 2014
Externally publishedYes

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Selection Bias
Birth Weight
Gestational Age
History

Keywords

  • causal diagrams
  • composite outcomes
  • paradox
  • selection bias

ASJC Scopus subject areas

  • Epidemiology

Cite this

Invited commentary : Composite outcomes as an attempt to escape from selection bias and related paradoxes. / Hernán, Miguel A.; Schisterman, Enrique F.; Hernández-Díaz, Sonia.

In: American Journal of Epidemiology, Vol. 179, No. 3, 02.2014, p. 368-370.

Research output: Contribution to journalArticle

Hernán, Miguel A. ; Schisterman, Enrique F. ; Hernández-Díaz, Sonia. / Invited commentary : Composite outcomes as an attempt to escape from selection bias and related paradoxes. In: American Journal of Epidemiology. 2014 ; Vol. 179, No. 3. pp. 368-370.
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