Investigation of low-contrast tumor detection in algorithm-enabled low-dose CBCT

Junguo Bian, Xiao Han, Emil Y. Sidky, Jeffrey H. Siewerdsen, Xiaochuan Pan

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Flat-panel-based X-ray cone-beam computed tomography (CBCT) can provide images of high utility in medical applications such as image-guided surgery and radiotherapy by offering location and contrast information concerning the target and surrounding region. A potential issue in these applications of CBCT is the imaging dose involved because repeated scans are necessary in the image-guided procedures. We investigate algorithm-enabled low-dose CBCT imaging for potential applications to image-guided surgery and radiotherapy procedures, involving detection of low-contrast tumor structures from sparse-view CBCT. Results of our study suggest that images of quality comparable to that of the FDK-reference image can be reconstructed from data much less than full data currently used.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposuim and Medical Imaging Conference, NSS/MIC 2010
Pages3479-3482
Number of pages4
DOIs
StatePublished - Dec 1 2010
Event2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010 - Knoxville, TN, United States
Duration: Oct 30 2010Nov 6 2010

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2010 IEEE Nuclear Science Symposium, Medical Imaging Conference, NSS/MIC 2010 and 17th International Workshop on Room-Temperature Semiconductor X-ray and Gamma-ray Detectors, RTSD 2010
CountryUnited States
CityKnoxville, TN
Period10/30/1011/6/10

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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    Bian, J., Han, X., Sidky, E. Y., Siewerdsen, J. H., & Pan, X. (2010). Investigation of low-contrast tumor detection in algorithm-enabled low-dose CBCT. In IEEE Nuclear Science Symposuim and Medical Imaging Conference, NSS/MIC 2010 (pp. 3479-3482). [5874453] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2010.5874453