Investigation of executive function change following anterior temporal lobectomy: Selective normalization of verbal fluency

Roy C. Martin, Stephen M. Sawrie, Robert Edwards, David L Roth, Edward Faught, Ruben I. Kuzniecky, Richard B. Morawetz, Frank G. Gilliam

Research output: Contribution to journalArticle

Abstract

The nociferous cortex hypothesis predicts that electrophysiological normalization to distal extratemporal brain regions following anterior temporal lobectomy (ATL) will result in improvements in executive functioning. The present study examined the effects of seizure laterality and seizure control on executive function change. The authors administered the Wisconsin Card Sorting Test (WCST), Trails B, and the Controlled Oral Word Association Test to 174 temporal lobe epilepsy patients who underwent ATL. No significant changes were found on the WCST or Trails B tests, regardless of surgery side or seizure-free status. However, verbal fluency significantly improved in seizure-free patients. Findings were consistent with the nociferous cortex hypothesis suggesting selective executive function improvement following ATL. These findings are discussed in terms of recent research demonstrating extrahippocampal metabolic normalization following surgery.

Original languageEnglish (US)
Pages (from-to)501-508
Number of pages8
JournalNeuropsychology
Volume14
Issue number4
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Fingerprint

Anterior Temporal Lobectomy
Executive Function
Seizures
Word Association Tests
Temporal Lobe Epilepsy
Brain
Research

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology

Cite this

Investigation of executive function change following anterior temporal lobectomy : Selective normalization of verbal fluency. / Martin, Roy C.; Sawrie, Stephen M.; Edwards, Robert; Roth, David L; Faught, Edward; Kuzniecky, Ruben I.; Morawetz, Richard B.; Gilliam, Frank G.

In: Neuropsychology, Vol. 14, No. 4, 01.01.2000, p. 501-508.

Research output: Contribution to journalArticle

Martin, RC, Sawrie, SM, Edwards, R, Roth, DL, Faught, E, Kuzniecky, RI, Morawetz, RB & Gilliam, FG 2000, 'Investigation of executive function change following anterior temporal lobectomy: Selective normalization of verbal fluency', Neuropsychology, vol. 14, no. 4, pp. 501-508. https://doi.org/10.1037/0894-4105.14.4.501
Martin, Roy C. ; Sawrie, Stephen M. ; Edwards, Robert ; Roth, David L ; Faught, Edward ; Kuzniecky, Ruben I. ; Morawetz, Richard B. ; Gilliam, Frank G. / Investigation of executive function change following anterior temporal lobectomy : Selective normalization of verbal fluency. In: Neuropsychology. 2000 ; Vol. 14, No. 4. pp. 501-508.
@article{6322dafc505a4af6b73b17c72fec57f8,
title = "Investigation of executive function change following anterior temporal lobectomy: Selective normalization of verbal fluency",
abstract = "The nociferous cortex hypothesis predicts that electrophysiological normalization to distal extratemporal brain regions following anterior temporal lobectomy (ATL) will result in improvements in executive functioning. The present study examined the effects of seizure laterality and seizure control on executive function change. The authors administered the Wisconsin Card Sorting Test (WCST), Trails B, and the Controlled Oral Word Association Test to 174 temporal lobe epilepsy patients who underwent ATL. No significant changes were found on the WCST or Trails B tests, regardless of surgery side or seizure-free status. However, verbal fluency significantly improved in seizure-free patients. Findings were consistent with the nociferous cortex hypothesis suggesting selective executive function improvement following ATL. These findings are discussed in terms of recent research demonstrating extrahippocampal metabolic normalization following surgery.",
author = "Martin, {Roy C.} and Sawrie, {Stephen M.} and Robert Edwards and Roth, {David L} and Edward Faught and Kuzniecky, {Ruben I.} and Morawetz, {Richard B.} and Gilliam, {Frank G.}",
year = "2000",
month = "1",
day = "1",
doi = "10.1037/0894-4105.14.4.501",
language = "English (US)",
volume = "14",
pages = "501--508",
journal = "Neuropsychology",
issn = "0894-4105",
publisher = "American Psychological Association Inc.",
number = "4",

}

TY - JOUR

T1 - Investigation of executive function change following anterior temporal lobectomy

T2 - Selective normalization of verbal fluency

AU - Martin, Roy C.

AU - Sawrie, Stephen M.

AU - Edwards, Robert

AU - Roth, David L

AU - Faught, Edward

AU - Kuzniecky, Ruben I.

AU - Morawetz, Richard B.

AU - Gilliam, Frank G.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - The nociferous cortex hypothesis predicts that electrophysiological normalization to distal extratemporal brain regions following anterior temporal lobectomy (ATL) will result in improvements in executive functioning. The present study examined the effects of seizure laterality and seizure control on executive function change. The authors administered the Wisconsin Card Sorting Test (WCST), Trails B, and the Controlled Oral Word Association Test to 174 temporal lobe epilepsy patients who underwent ATL. No significant changes were found on the WCST or Trails B tests, regardless of surgery side or seizure-free status. However, verbal fluency significantly improved in seizure-free patients. Findings were consistent with the nociferous cortex hypothesis suggesting selective executive function improvement following ATL. These findings are discussed in terms of recent research demonstrating extrahippocampal metabolic normalization following surgery.

AB - The nociferous cortex hypothesis predicts that electrophysiological normalization to distal extratemporal brain regions following anterior temporal lobectomy (ATL) will result in improvements in executive functioning. The present study examined the effects of seizure laterality and seizure control on executive function change. The authors administered the Wisconsin Card Sorting Test (WCST), Trails B, and the Controlled Oral Word Association Test to 174 temporal lobe epilepsy patients who underwent ATL. No significant changes were found on the WCST or Trails B tests, regardless of surgery side or seizure-free status. However, verbal fluency significantly improved in seizure-free patients. Findings were consistent with the nociferous cortex hypothesis suggesting selective executive function improvement following ATL. These findings are discussed in terms of recent research demonstrating extrahippocampal metabolic normalization following surgery.

UR - http://www.scopus.com/inward/record.url?scp=85047676655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047676655&partnerID=8YFLogxK

U2 - 10.1037/0894-4105.14.4.501

DO - 10.1037/0894-4105.14.4.501

M3 - Article

AN - SCOPUS:85047676655

VL - 14

SP - 501

EP - 508

JO - Neuropsychology

JF - Neuropsychology

SN - 0894-4105

IS - 4

ER -