Invasive Primary Cutaneous Phycomycosis in Diabetic Leg Ulcers

J. Walton Tomford, Diana Whittlesey, Jerrold J. Ellner, Joseph F. Tomashefski

Research output: Contribution to journalArticlepeer-review


Two cases of cutaneous phycomycosis in the form of diabetic leg ulcers were diagnosed by culture and biopsy demonstration of invasive fungal infection. The first patient had an infected vesicular skin lesion. Systemic amphotericin B therapy and repeated debridement were curative. A posttraumatic leg ulcer developed in the second patient in the setting of hyperglycemia and renal insufficiency. Aggressive infection necessitated a curative amputation. Phycomycetes can cause or complicate diabetic leg ulcers and such infections may require biopsy for early recognition and subsequent successful therapy.

Original languageEnglish (US)
Pages (from-to)770-771
Number of pages2
JournalArchives of Surgery
Issue number6
StatePublished - 1980

ASJC Scopus subject areas

  • Surgery


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