Invasive Aspergillosis

Stephen D. Prystowsky, Bert Vogelstein, David S. Ettinger, William G. Merz, Herbert Kaizer, Virginia I. Sulica, William H. Zinkham

Research output: Contribution to journalArticlepeer-review


There is an increasing frequency of mycotic infections in patients with leukemia and other hematologic neoplasia.1 2 3 Aspergillosis is second only to candidiasis in frequency of opportunistic fungal disease among such patients.2 3 4 5 6 Invasive aspergillosis is difficult to diagnose and is often lethal in the immunosuppressed host.5,7 Blood cultures3,8 and serologic tests9 are usually negative with systemic disease. Skin lesions are infrequently reported in large series of patients with invasive aspergillosis3,7,10,11; however, we have observed cutaneous involvement in four patients during the past two years. The purpose of this paper is to describe the characteristic morphology of the skin lesions in.

Original languageEnglish (US)
Pages (from-to)655-658
Number of pages4
JournalNew England Journal of Medicine
Issue number12
StatePublished - Sep 16 1976

ASJC Scopus subject areas

  • Medicine(all)


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