Invasive amebiasis and ameboma formation presenting as a rectal mass

An uncommon case of malignant masquerrade at western medical center

Rosemarie E. Hardin, George S. Ferzli, Michael E. Zenilman, Pratap K. Gadangi, Wilbur B. Bowne

Research output: Contribution to journalArticle

Abstract

A 54-year-old man presented with rectal pain and bleeding secondary to ulcerated, necrotic rectal and cecal masses that resembled colorectal carcinoma upon colonoscopy. These masses were later determined to be benign amebomas caused by invasive Entamoeba histolytica, which regressed completely with medical therapy. In Western countries, the occurrence of invasive protozoan infection with formation of amebomas is very rare and can mistakenly masquerade as a neoplasm. Not surprisingly, there have been very few cases reported of this clinical entity within the United States. Moreover, we report a patient that had an extremely rare occurrence of two synchronous lesions, one involving the rectum and the other situated in the cecum. We review the current literature on the pathogenesis of invasive E. histolytica infection and ameboma formation, as well as management of this rare disease entity at a western medical center.

Original languageEnglish (US)
Pages (from-to)5659-5661
Number of pages3
JournalWorld Journal of Gastroenterology
Volume13
Issue number42
StatePublished - Nov 14 2007
Externally publishedYes

Fingerprint

Amebiasis
Entamoeba histolytica
Protozoan Infections
Cecum
Colonoscopy
Rare Diseases
Rectum
Colorectal Neoplasms
Hemorrhage
Pain
Infection
Neoplasms
Therapeutics

Keywords

  • Amebic dysentery
  • Ameboma
  • Entameoba histolytica
  • Invasive amebiasis
  • Rectal emeboma

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Invasive amebiasis and ameboma formation presenting as a rectal mass : An uncommon case of malignant masquerrade at western medical center. / Hardin, Rosemarie E.; Ferzli, George S.; Zenilman, Michael E.; Gadangi, Pratap K.; Bowne, Wilbur B.

In: World Journal of Gastroenterology, Vol. 13, No. 42, 14.11.2007, p. 5659-5661.

Research output: Contribution to journalArticle

Hardin, Rosemarie E. ; Ferzli, George S. ; Zenilman, Michael E. ; Gadangi, Pratap K. ; Bowne, Wilbur B. / Invasive amebiasis and ameboma formation presenting as a rectal mass : An uncommon case of malignant masquerrade at western medical center. In: World Journal of Gastroenterology. 2007 ; Vol. 13, No. 42. pp. 5659-5661.
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