Abstract
The most common procedure for isolating genes that predispose to a certain disease is positional cloning. This process is initiated by mapping the responsible gene to its location on a chromosome linked to the disease. Successive cloning of the region results in the isolation of candidate genes. Finally, identification of mutations by mutational analysis points to the correct gene.
Original language | English (US) |
---|---|
Pages (from-to) | 116-118 |
Number of pages | 3 |
Journal | Clinical and Experimental Allergy, Supplement |
Volume | 25 |
Issue number | 2 |
State | Published - 1995 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology