The most common procedure for isolating genes that predispose to a certain disease is positional cloning. This process is initiated by mapping the responsible gene to its location on a chromosome linked to the disease. Successive cloning of the region results in the isolation of candidate genes. Finally, identification of mutations by mutational analysis points to the correct gene.
|Original language||English (US)|
|Number of pages||3|
|Journal||Clinical and Experimental Allergy, Supplement|
|State||Published - Jan 1 1995|
ASJC Scopus subject areas
- Immunology and Allergy