Abstract
Purpose: To study the effects of intravitreal injection (IVI) of expansile gas for early macular holes (EMH). Methods: Prospective interventional case series. Twelve eyes of 12 patients with EMH (stage 2) underwent IVI of perfluoropropane 0.2 ml followed by 5 days' facedown positioning. Results: Six cases (50%) achieved vitreous-macula separation. Three cases (25%) had hole closure with vision improvement; one of them developed rhegmatogenous retinal detachment (RRD) and hole re-opening. Another case with persistent hole also developed RRD. Seven of the 9 cases without hole closure and the one where the hole re-opened had vitrectomy, all resulting in hole closure and vision improvement. Duration of symptoms had borderline significance for hole closure (p = 0.11) and subsequent visual improvement (p = 0.03). Conclusion: With its low success rate, IVI of gas may not be a good option for EMH. Complications include retinal detachment. The procedure seems to not affect hole closure with subsequent vitrectomy.
Original language | English (US) |
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Pages (from-to) | 159-166 |
Number of pages | 8 |
Journal | Ophthalmologica |
Volume | 228 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2012 |
Externally published | Yes |
Keywords
- Early macular hole
- Expansile gas
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems