Intravascular large B-cell lymphoma presenting as multiple stroke A case report

Muharrem Yunce, Nargiz Muganlinskaya, Stephen Selinger

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Introduction: Intravascular large B-cell lymphoma (IVLBCL) is an uncommon disease with a poor prognosis if not diagnosed early. It can present with central nervous system (CNS) manifestations. The diagnosis of IVCBCL is difficult to make given its varied clinical manifestations and the lack of a specific diagnostic modality. Case presentation: We report an interesting case of IVLBCL presenting as bilateral strokes. The diagnosis was made by a random skin biopsy, which confirmed IVLBCL. The patient was treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). Neurological symptoms improved with R-CHOP. Repeat magnetic resonance imaging (MRI) of the brain showed improvement of the prior lesions. Conclusion: IVLBCL is an aggressive disease with high mortality. Timely diagnosis and treatment can be lifesaving.

Original languageEnglish (US)
Article numbere12793
JournalMedicine (United States)
Issue number41
StatePublished - Oct 1 2018
Externally publishedYes


  • Skin biopsy
  • Stroke

ASJC Scopus subject areas

  • Medicine(all)


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