Intravascular catheter exchange and duration of candidemia

NIAID Mycoses Study Group, Candidemia Study Group, NIAID Mycoses Study Group, Candidemia Study Group, NIAID Mycoses Study Group, Candidemia Study Group, NIAID Mycoses Study Group, Candidemia Study Group, NIAID Mycoses Study Group, Candidemia Study Group, NIAID Mycoses Study Group, Candidemia Study Group, NIAID Mycoses Study Group, Candidemia Study Group

Research output: Contribution to journalArticlepeer-review

Abstract

During a comparative trial of amphotericin B vs. fluconazole for treatment of candidemia in nonneutropenic patients, data on the management of intravascular catheters were collected. Complete records were available for 91% of the 206 study patients. For the subset of patients with a catheter in place at the time of their first positive blood culture, removal and replacement of all intravascular catheters without exchange over a guidewire from a preexisting line on or before the first day the study drug was administered were associated with a reduction in the subsequent mean duration (±SE) of candidemia, from 5.6 ± 0.8 days to 2.6 ± 0.5 days (>P <.001).

Original languageEnglish (US)
Pages (from-to)994-996
Number of pages3
JournalClinical Infectious Diseases
Volume21
Issue number4
DOIs
StatePublished - Oct 1995

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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