Intratympanic gentamicin injections

Desi P. Schoo, Brian M. Lin, Yuri Agrawal

Research output: Contribution to journalArticlepeer-review


Office-based intratympanic gentamicin injections are an important treatment modality for the management of refractory vestibular symptoms in patients suffering from Meniere's disease. Taking advantage of gentamicin's preferential vestibulotoxicity, chemical labyrinthectomy can be performed. Preprocedural counseling is necessary to ensure that patients have failed symptom control with maximal, non-ablative treatment options, including diet/lifestyle modification, diuretics and intratympanic steroid injections. Additionally, they should be familiar with the risk of hearing loss, and the likely continuation of non-vestibular aural symptoms. With appropriate dosing and monitoring, relief from vestibular symptoms may be achieved in up to 90% of patients while limiting risk to hearing.

Original languageEnglish (US)
Pages (from-to)99-103
Number of pages5
JournalOperative Techniques in Otolaryngology - Head and Neck Surgery
Issue number2
StatePublished - Jun 2021

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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