Intratympanic gentamicin injections

Desi P. Schoo; Brian M. Lin; Yuri Agrawal

doi:10.1016/j.otot.2021.05.006

Intratympanic gentamicin injections

Desi P. Schoo, Brian M. Lin, Yuri Agrawal

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Office-based intratympanic gentamicin injections are an important treatment modality for the management of refractory vestibular symptoms in patients suffering from Meniere's disease. Taking advantage of gentamicin's preferential vestibulotoxicity, chemical labyrinthectomy can be performed. Preprocedural counseling is necessary to ensure that patients have failed symptom control with maximal, non-ablative treatment options, including diet/lifestyle modification, diuretics and intratympanic steroid injections. Additionally, they should be familiar with the risk of hearing loss, and the likely continuation of non-vestibular aural symptoms. With appropriate dosing and monitoring, relief from vestibular symptoms may be achieved in up to 90% of patients while limiting risk to hearing.

Original language	English (US)
Pages (from-to)	99-103
Number of pages	5
Journal	Operative Techniques in Otolaryngology - Head and Neck Surgery
Volume	32
Issue number	2
DOIs	https://doi.org/10.1016/j.otot.2021.05.006
State	Published - Jun 2021

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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title = "Intratympanic gentamicin injections",

abstract = "Office-based intratympanic gentamicin injections are an important treatment modality for the management of refractory vestibular symptoms in patients suffering from Meniere's disease. Taking advantage of gentamicin's preferential vestibulotoxicity, chemical labyrinthectomy can be performed. Preprocedural counseling is necessary to ensure that patients have failed symptom control with maximal, non-ablative treatment options, including diet/lifestyle modification, diuretics and intratympanic steroid injections. Additionally, they should be familiar with the risk of hearing loss, and the likely continuation of non-vestibular aural symptoms. With appropriate dosing and monitoring, relief from vestibular symptoms may be achieved in up to 90% of patients while limiting risk to hearing.",

author = "Schoo, {Desi P.} and Lin, {Brian M.} and Yuri Agrawal",

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year = "2021",

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AU - Schoo, Desi P.

AU - Lin, Brian M.

AU - Agrawal, Yuri

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AB - Office-based intratympanic gentamicin injections are an important treatment modality for the management of refractory vestibular symptoms in patients suffering from Meniere's disease. Taking advantage of gentamicin's preferential vestibulotoxicity, chemical labyrinthectomy can be performed. Preprocedural counseling is necessary to ensure that patients have failed symptom control with maximal, non-ablative treatment options, including diet/lifestyle modification, diuretics and intratympanic steroid injections. Additionally, they should be familiar with the risk of hearing loss, and the likely continuation of non-vestibular aural symptoms. With appropriate dosing and monitoring, relief from vestibular symptoms may be achieved in up to 90% of patients while limiting risk to hearing.

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Intratympanic gentamicin injections

Abstract

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