Intrathecal gentamicin in treatment of bacterial meningitis

J. R. Graybill, J. Mann, P. Charache

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Two patients with bacterial meningitis were treated successfully with intrathecal gentamicin. Intraventricular instillation of the antibiotic was complicated by seizures and respiratory arrest in 1 patient. Lumbar instillation of gentamicin was uncomplicated in both patients and sterilized their cerebrospinal fluid, whereas comparable doses of polymyxin B failed to do so.

Original languageEnglish (US)
Pages (from-to)51-56
Number of pages6
JournalJohns Hopkins Medical Journal
Issue number1
StatePublished - 1973

ASJC Scopus subject areas

  • Medicine(all)


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