TY - JOUR
T1 - Intratendinous injection of platelet-rich plasma under US guidance to treat tendinopathy
T2 - A long-term pilot study
AU - Dallaudière, Benjamin
AU - Pesquer, Lionel
AU - Meyer, Philippe
AU - Silvestre, Alain
AU - Perozziello, Anne
AU - Peuchant, Alain
AU - Durieux, Marie Hélène Moreau
AU - Loriaut, Philippe
AU - Hummel, Vincent
AU - Boyer, Patrick
AU - Schouman-Claeys, Elisabeth
AU - Serfaty, Jean Michel
PY - 2014
Y1 - 2014
N2 - Purpose To assess the potential therapeutic effect of intratendinous injection of platelet-rich plasma (PRP) under ultrasound (US) guidance to treat tendon tears and tendinosis in a pilot study with long-term follow-up. Materials and Methods The study included 408 consecutive patients referred for treatment by PRP injection of tendinopathy in the upper (medial and lateral epicondylar tendons) and the lower (patellar, Achilles, hamstring and adductor longus, and peroneal tendons) limb who received a single intratendinous injection of PRP under US guidance. Clinical and US data were retrospectively collected for each anatomic compartment for upper and lower limbs before treatment (baseline) and 6 weeks after treatment. Late clinical data without US were collected until 32 months after the procedure (mean, 20.2 months). The McNemar test and regression model were used to compare clinical and US data. Results QuickDASH score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and residual US size of lesions were significantly lower after intratendinous injection of PRP under US guidance at 6 weeks and during long-term follow-up compared with baseline (P .29). No clinical complication was reported during follow-up. Conclusions Intratendinous injection of PRP under US guidance appears to allow rapid tendon healing and is well tolerated.
AB - Purpose To assess the potential therapeutic effect of intratendinous injection of platelet-rich plasma (PRP) under ultrasound (US) guidance to treat tendon tears and tendinosis in a pilot study with long-term follow-up. Materials and Methods The study included 408 consecutive patients referred for treatment by PRP injection of tendinopathy in the upper (medial and lateral epicondylar tendons) and the lower (patellar, Achilles, hamstring and adductor longus, and peroneal tendons) limb who received a single intratendinous injection of PRP under US guidance. Clinical and US data were retrospectively collected for each anatomic compartment for upper and lower limbs before treatment (baseline) and 6 weeks after treatment. Late clinical data without US were collected until 32 months after the procedure (mean, 20.2 months). The McNemar test and regression model were used to compare clinical and US data. Results QuickDASH score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, and residual US size of lesions were significantly lower after intratendinous injection of PRP under US guidance at 6 weeks and during long-term follow-up compared with baseline (P .29). No clinical complication was reported during follow-up. Conclusions Intratendinous injection of PRP under US guidance appears to allow rapid tendon healing and is well tolerated.
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U2 - 10.1016/j.jvir.2014.01.026
DO - 10.1016/j.jvir.2014.01.026
M3 - Article
C2 - 24656590
AN - SCOPUS:84899088969
SN - 1051-0443
VL - 25
SP - 717
EP - 723
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 5
ER -