Intrapancreatic accessory spleen: A case report and review of literature

Research output: Contribution to journalArticle

Abstract

Intrapancreatic accessory spleen is not an uncommon entity and usually located in the tail of the pancreas. Most of them are asymptomatic and incidental findings on radiologic study or at autopsy. On imaging study, it appears to be a well-defined, solitary, and hypervascular lesion; therefore, it may be confused with pancreatic neoplasms, such as neuroendocrine neoplasm, well-differentiated adenocarcinoma, solid pseudopapillary tumor, or metastatic tumor to the pancreas. As such, the diagnostic fine-needle aspiration biopsy of the lesion may be performed. Several case reports describing cytological features of the lesion have been published in recent years. Among them, the most commonly identified cytological findings are sheets of a heterogeneous population of lymphocytes and prominent traversing blood vessels. Herein, we report an unusual EUS-FNA case of intrapancreatic accessory spleen. In addition to above previously well-described cytological features, our case revealed many cells with fine granular chromatin and areas with pseudo rosette-like architecture, mimicking and engendering the differential diagnosis of pancreatic neuroendocrine tumors. Although cytological findings of our case are rare, they may extend our current knowledge and provide additional differential diagnostic information for this entity.

Original languageEnglish (US)
Pages (from-to)466-469
Number of pages4
JournalDiagnostic Cytopathology
Volume41
Issue number5
DOIs
StatePublished - May 2013

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Spleen
Pancreas
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Neoplasms
Incidental Findings
Neuroendocrine Tumors
Fine Needle Biopsy
Pancreatic Neoplasms
Chromatin
Blood Vessels
Autopsy
Adenocarcinoma
Differential Diagnosis
Lymphocytes
Population

Keywords

  • accessory spleen
  • fine-needle aspiration cytology
  • intrapancreas

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

Intrapancreatic accessory spleen : A case report and review of literature. / Rodriguez, Erika; Netto, George; Li, Qing Kay.

In: Diagnostic Cytopathology, Vol. 41, No. 5, 05.2013, p. 466-469.

Research output: Contribution to journalArticle

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