TY - JOUR
T1 - Intraoperative Radiographic Assessment of Bone Resection Margins During Mandibulectomy
T2 - A Case Series
AU - Shan, Alan
AU - Boahene, Kofi
AU - Pitman, Karen T.
AU - Blanco, Ray G.
N1 - Funding Information:
David Chen, MD, Melanie Benton, MS, PA (ASCP), Mary Kay Pogar, MS, PA (ASCP), Kelly Bair, MS, PA (ASCP), Robert Palermo, MD, Chairman Department of Pathology and Laboratory. The author(s) received no financial support for the research, authorship, and/or publication of this article.
Publisher Copyright:
© The Author(s) 2019.
PY - 2021/9
Y1 - 2021/9
N2 - Background and Purpose: Mandibulectomy remains the treatment of choice for oral cavity squamous cell carcinoma with infiltration of bone and for benign tumors with full mandibular thickness involvement. Although bone resection margins are critical for patient outcomes, intraoperative immediate bone margins assessment is inadequate, and few alternative options have been described. The purpose of this study was to describe the use of an existing intraoperative radiographic system for objective determination of bone resection margins during mandibulectomy. Methods: We conducted a retrospective case series of all patients at the Greater Baltimore Medical Center who underwent mandibulectomy and received intraoperative Faxitron radiography from January 1, 2016, to March 1, 2019. Patient characteristics including age, sex, diagnosis, tumor location, clinical and pathologic stage, procedure performed, and bone resection margins were reviewed. Results: A total of 10 patients underwent mandibulectomy with intraoperative radiography. Nine (90%) received surgery for squamous cell carcinoma, with 1 (10%) for ameloblastoma. Out of those with squamous cell carcinoma, tumor location varied, and all were clinically stage T4. Final pathologic margins were negative in all cases (10/10), though in 2 cases, close margins were assessed intraoperatively, leading to further resection or change in operative plan. Conclusion: Intraoperative radiographic assessment of bone resection margins is a promising technique, though further validation is required.
AB - Background and Purpose: Mandibulectomy remains the treatment of choice for oral cavity squamous cell carcinoma with infiltration of bone and for benign tumors with full mandibular thickness involvement. Although bone resection margins are critical for patient outcomes, intraoperative immediate bone margins assessment is inadequate, and few alternative options have been described. The purpose of this study was to describe the use of an existing intraoperative radiographic system for objective determination of bone resection margins during mandibulectomy. Methods: We conducted a retrospective case series of all patients at the Greater Baltimore Medical Center who underwent mandibulectomy and received intraoperative Faxitron radiography from January 1, 2016, to March 1, 2019. Patient characteristics including age, sex, diagnosis, tumor location, clinical and pathologic stage, procedure performed, and bone resection margins were reviewed. Results: A total of 10 patients underwent mandibulectomy with intraoperative radiography. Nine (90%) received surgery for squamous cell carcinoma, with 1 (10%) for ameloblastoma. Out of those with squamous cell carcinoma, tumor location varied, and all were clinically stage T4. Final pathologic margins were negative in all cases (10/10), though in 2 cases, close margins were assessed intraoperatively, leading to further resection or change in operative plan. Conclusion: Intraoperative radiographic assessment of bone resection margins is a promising technique, though further validation is required.
KW - intraoperative margins
KW - mandible margins
KW - mandibular imaging
KW - oncologic margins
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U2 - 10.1177/0145561319888034
DO - 10.1177/0145561319888034
M3 - Article
C2 - 31722565
AN - SCOPUS:85075380915
SN - 0145-5613
VL - 100
SP - 500S-504S
JO - Ear, Nose and Throat Journal
JF - Ear, Nose and Throat Journal
IS - 5_suppl
ER -