Intraoperative Perfusion Assessment in Mastectomy Skin Flaps

How Close are We to Preventing Complications?

Nima Khavanin, Cecil Qiu, Halley Darrach, Franca Kraenzlin, George Kokosis, Tinglu Han, Justin Michael Sacks

Research output: Contribution to journalReview article

Abstract

Background Mastectomy flap necrosis is the source of considerable morbidity and cost following breast reconstruction. A great deal of effort has been put forth to predicting and even preventing its incidence intraoperatively. Methods A review of the literature was performed evaluating the evidence of mastectomy skin flap perfusion technologies. Results Multiple technologies have leveraged spectroscopy and/or angiography to provide real-time assessment of flap perfusion, including indocyanine green, fluorescein, and light-based devices. Conclusion This manuscript endeavors to review the evidence on mastectomy skin flap perfusion analysis, highlighting the benefits, and downsides of the current technologies and identifying exciting areas of future research and development.

Original languageEnglish (US)
Pages (from-to)471-478
Number of pages8
JournalJournal of reconstructive microsurgery
Volume35
Issue number7
DOIs
StatePublished - Jan 1 2019

Fingerprint

Mastectomy
Perfusion
Technology
Skin
Indocyanine Green
Mammaplasty
Fluorescein
Spectrum Analysis
Angiography
Necrosis
Morbidity
Light
Costs and Cost Analysis
Equipment and Supplies
Incidence
Research

Keywords

  • flap
  • necrosis
  • perfusion
  • prevention
  • technology

ASJC Scopus subject areas

  • Surgery

Cite this

Intraoperative Perfusion Assessment in Mastectomy Skin Flaps : How Close are We to Preventing Complications? / Khavanin, Nima; Qiu, Cecil; Darrach, Halley; Kraenzlin, Franca; Kokosis, George; Han, Tinglu; Sacks, Justin Michael.

In: Journal of reconstructive microsurgery, Vol. 35, No. 7, 01.01.2019, p. 471-478.

Research output: Contribution to journalReview article

Khavanin, Nima ; Qiu, Cecil ; Darrach, Halley ; Kraenzlin, Franca ; Kokosis, George ; Han, Tinglu ; Sacks, Justin Michael. / Intraoperative Perfusion Assessment in Mastectomy Skin Flaps : How Close are We to Preventing Complications?. In: Journal of reconstructive microsurgery. 2019 ; Vol. 35, No. 7. pp. 471-478.
@article{0131263da74942bb93ff9cbf3ea02e25,
title = "Intraoperative Perfusion Assessment in Mastectomy Skin Flaps: How Close are We to Preventing Complications?",
abstract = "Background Mastectomy flap necrosis is the source of considerable morbidity and cost following breast reconstruction. A great deal of effort has been put forth to predicting and even preventing its incidence intraoperatively. Methods A review of the literature was performed evaluating the evidence of mastectomy skin flap perfusion technologies. Results Multiple technologies have leveraged spectroscopy and/or angiography to provide real-time assessment of flap perfusion, including indocyanine green, fluorescein, and light-based devices. Conclusion This manuscript endeavors to review the evidence on mastectomy skin flap perfusion analysis, highlighting the benefits, and downsides of the current technologies and identifying exciting areas of future research and development.",
keywords = "flap, necrosis, perfusion, prevention, technology",
author = "Nima Khavanin and Cecil Qiu and Halley Darrach and Franca Kraenzlin and George Kokosis and Tinglu Han and Sacks, {Justin Michael}",
year = "2019",
month = "1",
day = "1",
doi = "10.1055/s-0039-1679958",
language = "English (US)",
volume = "35",
pages = "471--478",
journal = "Journal of Reconstructive Microsurgery",
issn = "0743-684X",
publisher = "Thieme Medical Publishers",
number = "7",

}

TY - JOUR

T1 - Intraoperative Perfusion Assessment in Mastectomy Skin Flaps

T2 - How Close are We to Preventing Complications?

AU - Khavanin, Nima

AU - Qiu, Cecil

AU - Darrach, Halley

AU - Kraenzlin, Franca

AU - Kokosis, George

AU - Han, Tinglu

AU - Sacks, Justin Michael

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background Mastectomy flap necrosis is the source of considerable morbidity and cost following breast reconstruction. A great deal of effort has been put forth to predicting and even preventing its incidence intraoperatively. Methods A review of the literature was performed evaluating the evidence of mastectomy skin flap perfusion technologies. Results Multiple technologies have leveraged spectroscopy and/or angiography to provide real-time assessment of flap perfusion, including indocyanine green, fluorescein, and light-based devices. Conclusion This manuscript endeavors to review the evidence on mastectomy skin flap perfusion analysis, highlighting the benefits, and downsides of the current technologies and identifying exciting areas of future research and development.

AB - Background Mastectomy flap necrosis is the source of considerable morbidity and cost following breast reconstruction. A great deal of effort has been put forth to predicting and even preventing its incidence intraoperatively. Methods A review of the literature was performed evaluating the evidence of mastectomy skin flap perfusion technologies. Results Multiple technologies have leveraged spectroscopy and/or angiography to provide real-time assessment of flap perfusion, including indocyanine green, fluorescein, and light-based devices. Conclusion This manuscript endeavors to review the evidence on mastectomy skin flap perfusion analysis, highlighting the benefits, and downsides of the current technologies and identifying exciting areas of future research and development.

KW - flap

KW - necrosis

KW - perfusion

KW - prevention

KW - technology

UR - http://www.scopus.com/inward/record.url?scp=85070995988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85070995988&partnerID=8YFLogxK

U2 - 10.1055/s-0039-1679958

DO - 10.1055/s-0039-1679958

M3 - Review article

VL - 35

SP - 471

EP - 478

JO - Journal of Reconstructive Microsurgery

JF - Journal of Reconstructive Microsurgery

SN - 0743-684X

IS - 7

ER -