TY - JOUR
T1 - Intraocular Schwannoma
AU - You, Jae Young
AU - Finger, Paul T.
AU - Iacob, Codrin
AU - McCormick, Steven A.
AU - Milman, Tatyana
N1 - Funding Information:
The authors report no proprietary or commercial interest in any product mentioned or concept discussed in this article. Publication of this article was supported (in part) by The Eye Cancer Foundation, Inc. ( http://eyecancerfoundation.net ) and the Ophthalmic Pathology Research Fund.
Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/1
Y1 - 2013/1
N2 - Schwannoma is a proliferation of neoplastic Schwann cells. Whereas schwannomas of the head and neck region are common, intraocular tissues are rarely affected. Uveal schwannoma has been aptly called a " pseudomelanoma" , reflecting the difficulty in its clinical distinction from uveal malignant melanoma. Most of our current knowledge on intraocular schwannoma is limited to case reports, short case series, and non-comprehensive literature reviews. Three isolated reports of uveal schwannoma with extrascleral extension exist in literature, but the prognostic significance of this growth pattern is unknown. We present a patient with choroidal schwannoma with extrascleral extension and review 46 previously reported cases of uveal schwannomas to delineate clinical and pathologic characteristics of these intraocular tumors with a specific emphasis on schwannoma with extraocular extension.
AB - Schwannoma is a proliferation of neoplastic Schwann cells. Whereas schwannomas of the head and neck region are common, intraocular tissues are rarely affected. Uveal schwannoma has been aptly called a " pseudomelanoma" , reflecting the difficulty in its clinical distinction from uveal malignant melanoma. Most of our current knowledge on intraocular schwannoma is limited to case reports, short case series, and non-comprehensive literature reviews. Three isolated reports of uveal schwannoma with extrascleral extension exist in literature, but the prognostic significance of this growth pattern is unknown. We present a patient with choroidal schwannoma with extrascleral extension and review 46 previously reported cases of uveal schwannomas to delineate clinical and pathologic characteristics of these intraocular tumors with a specific emphasis on schwannoma with extraocular extension.
KW - Benign nerve sheath tumor
KW - Choroidal neurilemmoma
KW - Choroidal schwannoma
KW - Intraocular neurilemmoma
KW - Intraocular schwannoma
KW - Pseudomelanoma
KW - Uveal neurilemmoma
KW - Uveal schwannoma
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U2 - 10.1016/j.survophthal.2012.04.003
DO - 10.1016/j.survophthal.2012.04.003
M3 - Review article
C2 - 22981398
AN - SCOPUS:84870838167
VL - 58
SP - 77
EP - 85
JO - Survey of Ophthalmology
JF - Survey of Ophthalmology
SN - 0039-6257
IS - 1
ER -