Intraocular Schwannoma

Jae Young You, Paul T. Finger, Codrin Iacob, Steven A. McCormick, Tatyana Milman

Research output: Contribution to journalReview articlepeer-review

Abstract

Schwannoma is a proliferation of neoplastic Schwann cells. Whereas schwannomas of the head and neck region are common, intraocular tissues are rarely affected. Uveal schwannoma has been aptly called a " pseudomelanoma" , reflecting the difficulty in its clinical distinction from uveal malignant melanoma. Most of our current knowledge on intraocular schwannoma is limited to case reports, short case series, and non-comprehensive literature reviews. Three isolated reports of uveal schwannoma with extrascleral extension exist in literature, but the prognostic significance of this growth pattern is unknown. We present a patient with choroidal schwannoma with extrascleral extension and review 46 previously reported cases of uveal schwannomas to delineate clinical and pathologic characteristics of these intraocular tumors with a specific emphasis on schwannoma with extraocular extension.

Original languageEnglish (US)
Pages (from-to)77-85
Number of pages9
JournalSurvey of ophthalmology
Volume58
Issue number1
DOIs
StatePublished - Jan 1 2013

Keywords

  • Benign nerve sheath tumor
  • Choroidal neurilemmoma
  • Choroidal schwannoma
  • Intraocular neurilemmoma
  • Intraocular schwannoma
  • Pseudomelanoma
  • Uveal neurilemmoma
  • Uveal schwannoma

ASJC Scopus subject areas

  • Ophthalmology

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