In a double blind study no significant difference was found in intraocular pressure control, mean pressure or comparative binocular intraocular pressure difference between pilocarpine in adsorbobase compared to pilocarpine in 0.5% hydroxypropylmethylcellulose solution. Intraocular pressure control was achieved on fewer than 60% of visits using pilocarpine twice daily in either of the 2 vehicles. While pilocarpine retained some residual hypotensive effect 12 hours after application, twice-daily dosage with the solutions tested gave inadequate control for clinical usefulness.
|Original language||English (US)|
|Number of pages||4|
|Journal||Annals of ophthalmology|
|State||Published - Dec 1 1977|
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