Intramedullary Ewing sarcoma of the spinal cord: Consequences of molecular diagnostics

Robert J. Weil, Zhengping Zhuang, Svetlana Pack, Shimareet Kumar, Lee Helman, Brian G. Fuller, Crystall L. Mackall, Edward H. Oldfield

Research output: Contribution to journalArticle

Abstract

Molecular biological techniques have begun to transform modern medicine. These techniques have shown promise in the pathological diagnosis of difficult or uncommon tumors. Accurate molecular diagnosis of the small round-cell tumors, for example, is especially important because divergent therapies may be required to eradicate such disparate lesions as neuroblastoma, lymphoma, rhabdomyosarcoma, central primitive neuroectodermal tumors/medulloblastoma, or Ewing sarcoma (ES). The authors present an unusual case of a primary, extraosseous ES arising from the intramedullary spinal cord, in which molecular studies were required for specific diagnosis and therapeutic guidance.

Original languageEnglish (US)
Pages (from-to)270-275
Number of pages6
JournalJournal of neurosurgery
Volume95
Issue number2 SUPPL.
DOIs
StatePublished - 2001

Keywords

  • Chemotherapy
  • Chromosomal translocation
  • Ewing sarcoma
  • Radiation therapy
  • Spinal cord

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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  • Cite this

    Weil, R. J., Zhuang, Z., Pack, S., Kumar, S., Helman, L., Fuller, B. G., Mackall, C. L., & Oldfield, E. H. (2001). Intramedullary Ewing sarcoma of the spinal cord: Consequences of molecular diagnostics. Journal of neurosurgery, 95(2 SUPPL.), 270-275. https://doi.org/10.3171/spi.2001.95.2.0270