Intracranial self-stimulation in 3-day-old rat pups

Timothy H Moran, Mark F. Lew, Elliott M. Blass

Research output: Contribution to journalArticle

Abstract

Three-day-old rat pups with electrodes directed at the medial forebrain bundle at the level of the lateral hypothalamic area were trained to push a paddle to receive electrical brain stimulation. Pups receiving stimulation that was contingent on lifting the paddle responded more frequently than did control pups and also learned a two-choice spatial discrimination task that was rewarded with brain stimulation. The experiments indicate that a neural substrate in the area of the medial forebrain bundle is involved in the central mediation of reinforcement in the rat pup.

Original languageEnglish (US)
Pages (from-to)1366-1368
Number of pages3
JournalScience
Volume214
Issue number4527
StatePublished - 1981

Fingerprint

Medial Forebrain Bundle
Self Stimulation
Lateral Hypothalamic Area
Deep Brain Stimulation
Electrodes
Brain
Reinforcement (Psychology)
Discrimination (Psychology)

ASJC Scopus subject areas

  • General

Cite this

Moran, T. H., Lew, M. F., & Blass, E. M. (1981). Intracranial self-stimulation in 3-day-old rat pups. Science, 214(4527), 1366-1368.

Intracranial self-stimulation in 3-day-old rat pups. / Moran, Timothy H; Lew, Mark F.; Blass, Elliott M.

In: Science, Vol. 214, No. 4527, 1981, p. 1366-1368.

Research output: Contribution to journalArticle

Moran, TH, Lew, MF & Blass, EM 1981, 'Intracranial self-stimulation in 3-day-old rat pups', Science, vol. 214, no. 4527, pp. 1366-1368.
Moran TH, Lew MF, Blass EM. Intracranial self-stimulation in 3-day-old rat pups. Science. 1981;214(4527):1366-1368.
Moran, Timothy H ; Lew, Mark F. ; Blass, Elliott M. / Intracranial self-stimulation in 3-day-old rat pups. In: Science. 1981 ; Vol. 214, No. 4527. pp. 1366-1368.
@article{53ca5e8140f84e608db1682dcf25dd84,
title = "Intracranial self-stimulation in 3-day-old rat pups",
abstract = "Three-day-old rat pups with electrodes directed at the medial forebrain bundle at the level of the lateral hypothalamic area were trained to push a paddle to receive electrical brain stimulation. Pups receiving stimulation that was contingent on lifting the paddle responded more frequently than did control pups and also learned a two-choice spatial discrimination task that was rewarded with brain stimulation. The experiments indicate that a neural substrate in the area of the medial forebrain bundle is involved in the central mediation of reinforcement in the rat pup.",
author = "Moran, {Timothy H} and Lew, {Mark F.} and Blass, {Elliott M.}",
year = "1981",
language = "English (US)",
volume = "214",
pages = "1366--1368",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "4527",

}

TY - JOUR

T1 - Intracranial self-stimulation in 3-day-old rat pups

AU - Moran, Timothy H

AU - Lew, Mark F.

AU - Blass, Elliott M.

PY - 1981

Y1 - 1981

N2 - Three-day-old rat pups with electrodes directed at the medial forebrain bundle at the level of the lateral hypothalamic area were trained to push a paddle to receive electrical brain stimulation. Pups receiving stimulation that was contingent on lifting the paddle responded more frequently than did control pups and also learned a two-choice spatial discrimination task that was rewarded with brain stimulation. The experiments indicate that a neural substrate in the area of the medial forebrain bundle is involved in the central mediation of reinforcement in the rat pup.

AB - Three-day-old rat pups with electrodes directed at the medial forebrain bundle at the level of the lateral hypothalamic area were trained to push a paddle to receive electrical brain stimulation. Pups receiving stimulation that was contingent on lifting the paddle responded more frequently than did control pups and also learned a two-choice spatial discrimination task that was rewarded with brain stimulation. The experiments indicate that a neural substrate in the area of the medial forebrain bundle is involved in the central mediation of reinforcement in the rat pup.

UR - http://www.scopus.com/inward/record.url?scp=0019770995&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019770995&partnerID=8YFLogxK

M3 - Article

C2 - 6975999

AN - SCOPUS:0019770995

VL - 214

SP - 1366

EP - 1368

JO - Science

JF - Science

SN - 0036-8075

IS - 4527

ER -