Intracranial hypertension

Eric M. Bershad, William E. Humphreis, Jose Suarez

Research output: Contribution to journalReview article

Abstract

Intracranial hypertension implies profoundly disturbed intracranial physiology. Although a shared manifestation of myriad neurological disorders of patients admitted in the intensive care unit (ICU), the pathways leading to intracranial hypertension vary by etiology. Acute elevation of the intracranial pressure is an emergency and may rapidly lead to brain death or a devastating neurological outcome if left untreated. Fortunately, with a firm grasp of the underlying pathophysiology and available treatments, one can optimize ICU-based management. Several integrated management paradigms have been used to treat intracranial hypertension. Regrettably, there is a dearth of randomized clinical trials to confirm the efficacy of even our most routine therapeutic strategies.

Original languageEnglish (US)
Pages (from-to)690-702
Number of pages13
JournalSeminars in Neurology
Volume28
Issue number5
DOIs
StatePublished - Nov 1 2008
Externally publishedYes

Fingerprint

Intracranial Hypertension
Intensive Care Units
Brain Death
Hand Strength
Nervous System Diseases
Emergencies
Randomized Controlled Trials
Therapeutics

Keywords

  • Brain injury
  • Cerebral edema
  • Elevated
  • Intracranial hypertension
  • Intracranial pressure

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Intracranial hypertension. / Bershad, Eric M.; Humphreis, William E.; Suarez, Jose.

In: Seminars in Neurology, Vol. 28, No. 5, 01.11.2008, p. 690-702.

Research output: Contribution to journalReview article

Bershad, EM, Humphreis, WE & Suarez, J 2008, 'Intracranial hypertension', Seminars in Neurology, vol. 28, no. 5, pp. 690-702. https://doi.org/10.1055/s-0028-1105968
Bershad, Eric M. ; Humphreis, William E. ; Suarez, Jose. / Intracranial hypertension. In: Seminars in Neurology. 2008 ; Vol. 28, No. 5. pp. 690-702.
@article{7b01c8d7a7cc4293a7b8e654ec0d02d3,
title = "Intracranial hypertension",
abstract = "Intracranial hypertension implies profoundly disturbed intracranial physiology. Although a shared manifestation of myriad neurological disorders of patients admitted in the intensive care unit (ICU), the pathways leading to intracranial hypertension vary by etiology. Acute elevation of the intracranial pressure is an emergency and may rapidly lead to brain death or a devastating neurological outcome if left untreated. Fortunately, with a firm grasp of the underlying pathophysiology and available treatments, one can optimize ICU-based management. Several integrated management paradigms have been used to treat intracranial hypertension. Regrettably, there is a dearth of randomized clinical trials to confirm the efficacy of even our most routine therapeutic strategies.",
keywords = "Brain injury, Cerebral edema, Elevated, Intracranial hypertension, Intracranial pressure",
author = "Bershad, {Eric M.} and Humphreis, {William E.} and Jose Suarez",
year = "2008",
month = "11",
day = "1",
doi = "10.1055/s-0028-1105968",
language = "English (US)",
volume = "28",
pages = "690--702",
journal = "Seminars in Neurology",
issn = "0271-8235",
publisher = "Thieme Medical Publishers",
number = "5",

}

TY - JOUR

T1 - Intracranial hypertension

AU - Bershad, Eric M.

AU - Humphreis, William E.

AU - Suarez, Jose

PY - 2008/11/1

Y1 - 2008/11/1

N2 - Intracranial hypertension implies profoundly disturbed intracranial physiology. Although a shared manifestation of myriad neurological disorders of patients admitted in the intensive care unit (ICU), the pathways leading to intracranial hypertension vary by etiology. Acute elevation of the intracranial pressure is an emergency and may rapidly lead to brain death or a devastating neurological outcome if left untreated. Fortunately, with a firm grasp of the underlying pathophysiology and available treatments, one can optimize ICU-based management. Several integrated management paradigms have been used to treat intracranial hypertension. Regrettably, there is a dearth of randomized clinical trials to confirm the efficacy of even our most routine therapeutic strategies.

AB - Intracranial hypertension implies profoundly disturbed intracranial physiology. Although a shared manifestation of myriad neurological disorders of patients admitted in the intensive care unit (ICU), the pathways leading to intracranial hypertension vary by etiology. Acute elevation of the intracranial pressure is an emergency and may rapidly lead to brain death or a devastating neurological outcome if left untreated. Fortunately, with a firm grasp of the underlying pathophysiology and available treatments, one can optimize ICU-based management. Several integrated management paradigms have been used to treat intracranial hypertension. Regrettably, there is a dearth of randomized clinical trials to confirm the efficacy of even our most routine therapeutic strategies.

KW - Brain injury

KW - Cerebral edema

KW - Elevated

KW - Intracranial hypertension

KW - Intracranial pressure

UR - http://www.scopus.com/inward/record.url?scp=58849123145&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58849123145&partnerID=8YFLogxK

U2 - 10.1055/s-0028-1105968

DO - 10.1055/s-0028-1105968

M3 - Review article

C2 - 19115175

AN - SCOPUS:58849123145

VL - 28

SP - 690

EP - 702

JO - Seminars in Neurology

JF - Seminars in Neurology

SN - 0271-8235

IS - 5

ER -