Intracranial hemorrhage at the onset of thrombotic thrombocytopenic purpura in an infant: Therapeutic approach and intensive care management

M. Piastra, V. CurrÒ, A. Chiaretti, L. Viola, L. Tortorolo, G. Polidori

Research output: Contribution to journalArticlepeer-review

Abstract

Thrombotic thrombocytopenic purpura (TTP) is quite rare in infancy and must be treated intensively as a life-threatening disease. Diffuse vascular thromboses may occur, and neurologic involvement is a cornerstone of the diagnosis of TTP. We describe a case of an infant who presented with a sudden cerebral hemorrhage and subsequently developed the typical clinical features of TTP. Emergency treatment in the Pediatric Intensive Care Unit (PICU) consisted of plasma therapy and exchange-transfusion (EXT) to arrest the intravascular process and the exsanguinating blood loss. Exchange-transfusion is a life-saving procedure that is rarely performed after the neonatal age.

Original languageEnglish (US)
Pages (from-to)42-45
Number of pages4
JournalPediatric emergency care
Volume17
Issue number1
DOIs
StatePublished - 2001
Externally publishedYes

Keywords

  • Cerebral hemorrhage
  • Exchange transfusion
  • Plasma therapy
  • Thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine

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