Intracranial aneurysm following radiation therapy during childhood for a brain tumor: Case report and review of the literature

Daniel M. Sciubba, Gary L. Gallia, Pablo Recinos, Ira M. Garonzik, Richard E. Clatterbuck

Research output: Contribution to journalArticlepeer-review

Abstract

Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle cerebral artery aneurysm developed 15 years after radiotherapy, which was given as adjuvant treatment following resection of a medulloblastoma. The patient underwent a craniotomy for microsurgical trapping of the aneurysm and was discharged without any neurological deficit. This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy.

Original languageEnglish (US)
Pages (from-to)134-139
Number of pages6
JournalJournal of neurosurgery
Volume105 PEDIATRICS
Issue numberSUPPL. 2
StatePublished - Aug 1 2006

Keywords

  • Intracranial aneurysm
  • Medulloblastoma
  • Pediatric neurosurgery
  • Radiation therapy
  • Vasculopathy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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