Intracranial aneurysm following radiation therapy during childhood for a brain tumor

Case report and review of the literature

Daniel Sciubba, Gary L Gallia, Pablo Recinos, Ira Garonzik, Richard E. Clatterbuck

Research output: Contribution to journalArticle

Abstract

Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle cerebral artery aneurysm developed 15 years after radiotherapy, which was given as adjuvant treatment following resection of a medulloblastoma. The patient underwent a craniotomy for microsurgical trapping of the aneurysm and was discharged without any neurological deficit. This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy.

Original languageEnglish (US)
Pages (from-to)134-139
Number of pages6
JournalJournal of Neurosurgery
Volume105 PEDIATRICS
Issue numberSUPPL. 2
StatePublished - Aug 2006

Fingerprint

Intracranial Aneurysm
Brain Neoplasms
Radiotherapy
Medulloblastoma
Craniotomy
Ionizing Radiation
Aneurysm
Blood Vessels
Thrombosis
Therapeutics

Keywords

  • Intracranial aneurysm
  • Medulloblastoma
  • Pediatric neurosurgery
  • Radiation therapy
  • Vasculopathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Intracranial aneurysm following radiation therapy during childhood for a brain tumor : Case report and review of the literature. / Sciubba, Daniel; Gallia, Gary L; Recinos, Pablo; Garonzik, Ira; Clatterbuck, Richard E.

In: Journal of Neurosurgery, Vol. 105 PEDIATRICS, No. SUPPL. 2, 08.2006, p. 134-139.

Research output: Contribution to journalArticle

Sciubba, Daniel ; Gallia, Gary L ; Recinos, Pablo ; Garonzik, Ira ; Clatterbuck, Richard E. / Intracranial aneurysm following radiation therapy during childhood for a brain tumor : Case report and review of the literature. In: Journal of Neurosurgery. 2006 ; Vol. 105 PEDIATRICS, No. SUPPL. 2. pp. 134-139.
@article{24a80bec5cbe4042a2ad66464d652836,
title = "Intracranial aneurysm following radiation therapy during childhood for a brain tumor: Case report and review of the literature",
abstract = "Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle cerebral artery aneurysm developed 15 years after radiotherapy, which was given as adjuvant treatment following resection of a medulloblastoma. The patient underwent a craniotomy for microsurgical trapping of the aneurysm and was discharged without any neurological deficit. This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy.",
keywords = "Intracranial aneurysm, Medulloblastoma, Pediatric neurosurgery, Radiation therapy, Vasculopathy",
author = "Daniel Sciubba and Gallia, {Gary L} and Pablo Recinos and Ira Garonzik and Clatterbuck, {Richard E.}",
year = "2006",
month = "8",
language = "English (US)",
volume = "105 PEDIATRICS",
pages = "134--139",
journal = "Journal of Neurosurgery",
issn = "0022-3085",
publisher = "American Association of Neurological Surgeons",
number = "SUPPL. 2",

}

TY - JOUR

T1 - Intracranial aneurysm following radiation therapy during childhood for a brain tumor

T2 - Case report and review of the literature

AU - Sciubba, Daniel

AU - Gallia, Gary L

AU - Recinos, Pablo

AU - Garonzik, Ira

AU - Clatterbuck, Richard E.

PY - 2006/8

Y1 - 2006/8

N2 - Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle cerebral artery aneurysm developed 15 years after radiotherapy, which was given as adjuvant treatment following resection of a medulloblastoma. The patient underwent a craniotomy for microsurgical trapping of the aneurysm and was discharged without any neurological deficit. This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy.

AB - Ionizing radiation therapy is associated with pathological vascular changes in intracranial vessels, most commonly in the form of vessel thrombosis and occlusion. The development of an intracranial aneurysm following such therapy, however, is far less common. In this report the authors describe a 24-year-old man in whom a distal middle cerebral artery aneurysm developed 15 years after radiotherapy, which was given as adjuvant treatment following resection of a medulloblastoma. The patient underwent a craniotomy for microsurgical trapping of the aneurysm and was discharged without any neurological deficit. This case serves to remind clinicians of the possibility, albeit rare, that intracranial aneurysms may form following cranial radiotherapy.

KW - Intracranial aneurysm

KW - Medulloblastoma

KW - Pediatric neurosurgery

KW - Radiation therapy

KW - Vasculopathy

UR - http://www.scopus.com/inward/record.url?scp=33748534151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748534151&partnerID=8YFLogxK

M3 - Article

VL - 105 PEDIATRICS

SP - 134

EP - 139

JO - Journal of Neurosurgery

JF - Journal of Neurosurgery

SN - 0022-3085

IS - SUPPL. 2

ER -