Intracellular and extracellular rhomboid shaped crystalline inclusions in a case of IgG lambda restricted plasma cell myeloma: A case report and review of the literature

Andres Matoso, Tina Rizack, Diana O. Treaba

Research output: Contribution to journalArticle

Abstract

The presence of crystalline inclusions in plasma cell myeloma is a rare phenomenon and cases have been reported with rod, needle, and rectangular shaped crystals. Here, we present a case of IgG lambda restricted plasma cell myeloma with rhomboid shaped intracellular crystalline inclusions and extracellular crystal depositions in the bone marrow. Since rhomboid crystal depositions can be seen in other clinical conditions such as pseudogout, this case invites consideration of plasma cell myeloma in the differential diagnosis of patients with rhomboid crystalline deposition in the bone marrow and in sites/organs other than the bone marrow.

Original languageEnglish (US)
Article number6
JournalDiagnostic Pathology
Volume5
Issue number1
DOIs
StatePublished - Feb 26 2010
Externally publishedYes

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Multiple Myeloma
Immunoglobulin G
Bone Marrow
Chondrocalcinosis
Needles
Differential Diagnosis

ASJC Scopus subject areas

  • Histology
  • Pathology and Forensic Medicine

Cite this

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